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- Design
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34 min
1. An introduction to randomization for clinical trials 1- Prof. William Rosenberger
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20 min
2. An introduction to randomization for clinical trials 2- Prof. William Rosenberger
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42 min
3. Randomisation, blinding and drug supply in interactive voice response trials- Mr. Damian McEntegart
- Analysis
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32 min
4. Design and conduct of non-inferiority trials- Prof. Valerie Durkalski-Mauldin
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37 min
5. Nonparametric covariate adjustment- Prof. Michael Akritas
- Theory
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43 min
6. Historical and ethical issues in trial design- Dr. J. Rosser Matthews
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52 min
7. Likelihood ratios and the strength of statistical evidence- Prof. Jeffrey Blume
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36 min
- Randomization, Masking and Allocation Concealment
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22 min
9. Detection of and adjustment for selection bias in randomized controlled clinical trials- Prof. Lieven Nils Kennes
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46 min
10. Innovative and effective subject randomization methods- Prof. Wenle Zhao
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12 min
11. Selection bias in studies with unequal allocation- Dr. Olga M. Kuznetsova
- Archived Lectures *These may not cover the latest advances in the field
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45 min
12. Design and conduct of equivalence trials- Prof. Valerie Durkalski-Mauldin
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19 min
13. Dose-finding trials in oncology- Prof. Anastasia Ivanova
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32 min
14. Allocation concealment, prediction and selection bias- Prof. David Torgerson
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41 min
15. Pseudo cluster randomization- Dr. George Borm
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26 min
16. Introduction to flexible, adaptive trial design- Dr. Cyrus Mehta
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30 min
17. Randomization in clinical trials- Prof. William Rosenberger
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35 min
18. Novel methods for randomizing- Dr. William Grant
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20 min
19. Permutation tests- Dr. YanYan Zhou
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59 min
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32 min
21. Multiple analyses in clinical trials- Prof. Lemuel Moye
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26 min
22. Handling of missing data in clinical trials- Dr. Linda Yau
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35 min
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24 min
24. N-of-1 randomized clinical trials- Prof. Patrick Onghena
Printable Handouts
Navigable Slide Index
- Introduction
- Background
- Selection bias
- Randomisation (1)
- Quasi-alternation
- True alternation
- Alternation and selection
- Randomisation (2)
- Subversion
- Foreknowledge of allocation
- Subversion - evidence
- Quantitative evidence
- Poor concealment
- Comparison of concealment
- Allocation concealment and sequence generation
- Concealment
- More evidence
- Case study (1)
- Case study (2)
- Mean ages of groups
- More examples
- Recent blocked trial
- What is wrong here?
- Problem?
- Concealment: recommendations
- Simple or restricted randomisation?
- Restricted allocation
- Blocking
- What is current practice?
- Restricted allocation and subversion
- Possible subversion
- Wither restricted allocation?
- Testing for subversion
- Prediction and cluster randomised controlled trials
- Cluster trials
- Consent bias
- Hip protector trial
- Review of cluster trials
- Review results
- Misleading trial
- Baseline characteristics
- Selection bias in recruitment
- What happened?
- UK BEAM trial
- UK BEAM selection bias
- UK BEAM participant recruitment
- UK BEAM
- Avoiding selection bias in cluster trials
- Selection bias in meta-analysis
- Selection bias in trials: summary
Topics Covered
- Introduction to selection bias
- Allocation methods
- Evidence for subversion bias
- Restricted or simple randomization
- Problems with cluster randomization
- Evidence for selection bias in cluster trials
Links
Series:
Categories:
Talk Citation
Torgerson, D. (2007, October 1). Allocation concealment, prediction and selection bias [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 19, 2024, from https://hstalks.com/bs/539/.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. David Torgerson has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
