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- Defining Retroviruses
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1. An introduction to retroviruses: replication strategy and genetics
- Dr. Jonathan Stoye
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2. Bovine leukemia virus
- Prof. Arsene Burny
- Dr. Lucas Willems
- The First Human Retroviruses
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3. The discovery of human retroviruses and how they cause disease
- Prof. Robert Gallo
- HIV - Peculiarities of its Genome
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4. HIV: peculiarities of its genome
- Dr. George Pavlakis
- HIV Transmission, Epidemiology and Public Health/Prevention Issues
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5. HIV/AIDS epidemiology, transmission, and risk factors
- Prof. William Blattner
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6. HIV prevention and public health issues: a global perspective
- Prof. Sten H. Vermund
- How HIV causes AIDS
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7. How HIV causes disease 1: identification and characterization of HIV
- Prof. Bruce Walker
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8. How HIV causes disease 2: immune responses to HIV infection
- Prof. Bruce Walker
- HIV Therapy - Now and the Future
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9. HIV therapy: taking advantage of progress
- Prof. Paul Volberding
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10. HIV cure: harnessing innate and adaptive strategies
- Prof. Luis Montaner
- Archived Lectures *These may not cover the latest advances in the field
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11. The first human retroviruses: the human T lymphotropic viruses (HTLVs)
- Prof. William Hall
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12. HIV preventive vaccines
- Prof. Andrew McMichael
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13. HIV/AIDS in the developing world: what can we do?
- Dr. Joseph O'Neill
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15. Antiretroviral therapy 2007, new concepts and lessons learned
- Prof. Robert Redfield
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16. What to do in therapy in the face of HIV drug resistance?
- Prof. Mark Wainberg
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17. Viral reservoirs, latency and mechanisms of HIV persistence
- Prof. Robert Siliciano
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18. HIV preintegration complexes
- Prof. Lee Ratner
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19. The discovery of ATL field expansion in 40 yrs
- Prof. Junji Yodoi
Printable Handouts
Navigable Slide Index
- Introduction
- Human retroviruses
- Endemic areas of HTLV-I infection
- HTLV-I: associated clinical disorders
- HAM/ TSP
- ATLL clinical/epidemiological features
- ATLL pathological and immunological features
- A flower cell
- Cutaneous infiltrates in ATLL (1)
- Cutaneous infiltrates in ATLL (2)
- Typical histopathological of lymphoma
- Cell proliferation and transformation by HTLV-I Tax
- HTLV-I Tax and NF-kappa B activation
- NF-kappa B activation in patients with ATLL
- Development of ATLL
- Established HTLV-I Tax-transgenic mouse models
- Generation of Tax transgenic mice
- Summary of initial study of transgenic mice
- Estimation of Tax DNA copy number
- Tax integration sites-genome walking analysis
- Gross pathological findings
- Histological findings (1)
- Histological findings (2)
- Peripheral blood: leukemic cells
- Histological findings: P. jiroveci pneumonia
- NF-kappa B activation in Tax Tg mice
- Transfer of Tg Tax ATLL disorder to SCID mice
- SCID mice peripheral blood
- SCID mice histology
- Flow cytometry analysis
- Effect of lck promoter on T-cell phenotype
- Affymetrix microarray data
- Conclusions (1)
- HTLV-II infection in American Indian populations
- HTLV-II infection in IDUs
- HTLV-II phylogenetic tree
- HTLV Tax heterogeneity
- HTLV-II molecular epidemiology
- HTLV type II: oncogenic properties of Tax
- Conclusions (2)
Topics Covered
- Human retroviruses
- HTLV-1
- HTLV-2
- Epidemiology of infection
- Clinical features of infection
- Adult T-cell leukemia/lymphoma (ATLL)
- Molecular pathogenesis of ATLL
- Transgenic mouse model of ATLL
Talk Citation
Hall, W. (2007, October 1). The first human retroviruses: the human T lymphotropic viruses (HTLVs) [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 5, 2024, from https://doi.org/10.69645/XNST4194.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. William Hall has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
The first human retroviruses: the human T lymphotropic viruses (HTLVs)
A selection of talks on Microbiology
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