• Introduction to the World of Hormones
• 45 min
  1. Introduction to hormones

  • Prof. Helen Henry
• The Reproductive Hormones
• 44 min
  2. Endocrinology of parturition

  • Dr. Errol Norwitz
• 54 min
  3. Menopausal hormone therapy

  • Prof. Hugh Taylor
• 53 min
  4. Understanding hormones: mechanisms of androgen receptor function in reproduction and cancer

  • Prof. Elizabeth Wilson
• Hormones in Calcium and Phosphorus Homeostasis
• 36 min
  5. Vitamin D endocrine system: basics

  • Prof. Anthony Norman
• 47 min
  6. Vitamin D endocrine system: mechanisms to produce biological responses

  • Prof. Anthony Norman
• 37 min
  7. Parathyroid hormone and parathyroid hormone-related protein

  • Prof. Robert Nissenson
• 51 min
  8. Hormonal influence on bone remodeling and its implications for the pathophysiology of osteoporosis

  • Prof. Stavros Manolagas
• Hormones and the Vasculature
• 52 min
  9. Vascular cell signaling by membrane estrogen receptors

  • Prof. Jeffrey Bender
• Hormones and Energy Metabolism
• 41 min
  10. Pathogenesis of the metabolic syndrome

  • Prof. Richard Bergman
• Hormones and Growth
• 31 min
  11. The growth hormone/insulin-like growth factor-1 axis in health and disease

  • Prof. Derek LeRoith
• Frontiers in Hormone Research
• 47 min
  12. Prevention of type 1 diabetes

  • Prof. Chantal Mathieu
• 27 min
  13. Actions of steroid hormones in the brain

  • Prof. Bruce McEwen
• 40 min
  14. Vitamin D and prostate cancer

  • Prof. David Feldman
• Archived Lectures *These may not cover the latest advances in the field
• 46 min
  15. G-protein coupled receptors: hormone membrane receptors

  • Prof. Stuart Sealfon
• 40 min
  16. Nuclear receptors: transcriptional functions

  • Prof. Nancy Weigel
  • Dr. Neil McKenna
• 60 min
  17. Steroid hormones and their receptors in breast cancer

  • Prof. JoEllen Welsh
• 44 min
  18. Nuclear receptor superfamily: structural insights into function

  • Prof. Dino Moras
• 53 min
  19. Receptor tyrosine kinases - function, families and evolution

  • Prof. Tony Hunter
• 58 min
  20. Can we prevent type I diabetes?

  • Prof. Chantal Mathieu
• 39 min
  21. Vitamin D endocrine system: VDR binding, nutrition and drugs development

  • Prof. Anthony Norman

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Number of postmenopausal women in the US
3. Menopause health risks
4. Outline
5. Why women initiate or continue ERT/HRT
6. Menopause: HRT benefits
7. Controversies in management
8. Women's health initiative (WHI) study
9. WHI E+P: background
10. WHI E-alone: background
11. WHI E+P: benefits and risks
12. WHI estrogen alone
13. WHI - drawbacks
14. Disease latency
15. WHI E+P: hip fracture
16. Heart disease
17. Factors that influence heart disease
18. Effect of estrogen on risk for CHD
19. Coronary artery atherosclerosis
20. HRT trial: CHD events
21. WHI E+P: risk of CHD
22. Life history of an atheroma
23. Importance of timing of intervention in primates
24. WHI: CHD and HT
25. Coronary events by age at baseline in WHI
26. E-alone: cardiovascular outcomes ages 50-59
27. CEE and coronary artery calcium at age 50-59
28. KEEPS trial
29. CHD events in the WHI E-only arm
30. Breast cancer
31. Review of studies published from 1975-2000
32. WHI results: breast cancer
33. WHI - ET arm: breast cancer
34. Meaning of risk of breast cancer detection
35. Time course for breast cancer development
36. WHI E+P: effect on risk of in situ breast cancer
37. Cumulative hazards for breast cancer
38. WHI results: mortality
39. Diseases with a long latency period
40. Low dose is recommended
41. Women's HOPE study
42. Women's HOPE study: total hip BMD
43. Conclusions

Topics Covered

• Menopause health risks
• Hormone therapy in perspective
• Reasons for continuing or initiating ERT/HRT
• HRT benefits
• Women's health initiative (WHI)
• Heart disease
• Effect of Estrogen on risk of CHD
• Breast cancer
• Increased risk of breast cancer detection is not the same as breast cancer mortality or causality
• The WHI did not consider disease latency
• Low doses are recommended
• Women's HOPE study

Links

Series:

• The World of Hormones

Categories:

• Reproduction & Development

Therapeutic Areas:

• Gynaecology & Obstetrics

Talk Citation

Publication History

• Published on December 1, 2007

Financial Disclosures

• Prof. Hugh Taylor has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.