Interviewer: Professor Anthony David, thank you very much for
taking the time to do this interview with us today to discuss
neuropsychiatric effects and exacerbations related to COVID-19.
First of all, regarding the link between COVID and neuropsychiatric disorders,
have there been any reported cases of any kind implicating
direct causality between COVID and the emergence of such disorders?
Prof. David: Thanks for that question.
This was a topic of a lot of interest
right at the beginning when we were just beginning to learn about this new virus.
I think it's true to say that the virus can enter the brain,
it can be detected in the brain and in
people who have unfortunately died of a COVID-related illness
it is occasionally found there post mortem,
but it is very rare.
So it very seldom does enter the brain,
and our normal tests for people in life (such as when we take spinal fluid),
very seldom contain the virus or even any kind of sign that the virus is there.
It suggests that any direct infection is not
really the main mechanism for any illness arising from COVID-19,
in terms of the brain,
neurological or psychiatric disorders.
The same isn't true of the lungs, for example.
How does it cause its effects?
The virus does have a big impact
on the blood circulation and the clotting of the blood.
Blockages to either large or small vessels, or inflammation around the vessels