• View the Talks
• 46 min
  1. Genetic defects and calcium

  • Prof. Tullio Pozzan
• 38 min
  2. Pancreatitis and calcium signaling

  • Prof. Ole Petersen
• 28 min
  3. Ca2+ alterations in familial Alzheimer's disease (FAD)

  • Dr. Paola Pizzo
• 48 min
  4. Ca2+ signaling alterations in Alzheimer's disease

  • Dr. Grace Stutzmann
• 30 min
  5. Nociception and alpha2delta3

  • Dr. Greg Neely
• 45 min
  6. Disease hot spots of ryanodine receptors

  • Dr. Filip Van Petegem
• 46 min
  7. Calcium channelopathies

  • Dr. David Friel
• 27 min
  8. Ca2+, the endoplasmic reticulum and cardiac pathology

  • Prof. Marek Michalak
• 47 min
  9. Mechanism-based therapies for heart failure and cardiac arrhythmias

  • Prof. Andrew Marks
• 49 min
  10. Store-operated Ca2+ entry and vascular smooth muscle remodeling

  • Prof. Mohamed Trebak
• 43 min
  11. Polycystins, calcium signaling and pathogenesis of polycystic kidney disease

  • Prof. Laura del Senno
• 21 min
  12. Acidocalcisomes: conserved from bacterial to human cells

  • Prof. Roberto Docampo
• 26 min
  13. Cellular signaling on host-malaria parasite interactions

  • Prof. Dr. Celia Regina da Silva Garcia
• 34 min
  14. Ca(v)1.3 and deafness

  • Dr. Amy Lee
• 38 min
  15. Immunodeficiencies and pathologies associated with mutations in STIM/ORAI

  • Dr. Thierry Capiod
• 31 min
  16. Vascular calcification location, formation and biological activity

  • Dr. Diane Proudfoot
• Archived Lectures *These may not cover the latest advances in the field
• 31 min
  17. Ca2+ channelopathies

  • Dr. David Friel

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Main actors in Ca2+ homeostasis mechanism
3. Calcium signalling: dynamics and homeostasis
4. Genetic disorders of Ca2+ channels and pumps (1)
5. Events involved in a muscle twitch
6. Membrane potential vs. time
7. Neuro-muscular junction
8. Multimolecular calcium signalling complexes
9. Arrangement of proteins in SR and T tubule
10. Sarcoplasmic reticulum
11. Malignant hyperthermia
12. Central core disease (CCD)
13. Brody disease
14. Organisation of cardiac calcium signalling
15. Arrithmogenic right ventricular dysplasia 2-ARVD2
16. Genetic disorders of Ca2+ channels and pumps (2)
17. Structure of voltage-gated Ca2+ channels
18. Familial hemiplegic migraine (FHM)
19. Golgi can also be a Ca2+ storage compartment
20. Hailey Hailey disease
21. Mutation in Orai1 causes immune deficiency
22. Summary

Topics Covered

• General concepts of calcium signaling
• Mechanisms of calcium extrusion/uptake
• Mechanisms of calcium release from the ER/SR
• General concepts about plasma membrane calcium channels
• Genetic defects of calcium release channels
• Genetic defects of plasma membrane calcium channels
• Genetic defects of calcium pumps
• Novel findings on genetic defects of store dependent calcium channels

Links

Series:

• Calcium Signaling I
• Calcium Signaling II

Categories:

• Biochemistry
• Cell Biology

Talk Citation

Publication History

• Published on October 1, 2007

Financial Disclosures

• Prof. Tullio Pozzan has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.