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1. Genetic defects and calcium
- Prof. Tullio Pozzan
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2. Pancreatitis and calcium signaling
- Prof. Ole Petersen
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3. Ca2+ alterations in familial Alzheimer's disease (FAD)
- Dr. Paola Pizzo
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4. Ca2+ signaling alterations in Alzheimer's disease
- Dr. Grace Stutzmann
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5. Nociception and alpha2delta3
- Dr. Greg Neely
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6. Disease hot spots of ryanodine receptors
- Dr. Filip Van Petegem
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7. Calcium channelopathies
- Dr. David Friel
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8. Ca2+, the endoplasmic reticulum and cardiac pathology
- Prof. Marek Michalak
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9. Mechanism-based therapies for heart failure and cardiac arrhythmias
- Prof. Andrew Marks
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10. Store-operated Ca2+ entry and vascular smooth muscle remodeling
- Prof. Mohamed Trebak
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11. Polycystins, calcium signaling and pathogenesis of polycystic kidney disease
- Prof. Laura del Senno
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12. Acidocalcisomes: conserved from bacterial to human cells
- Prof. Roberto Docampo
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13. Cellular signaling on host-malaria parasite interactions
- Prof. Dr. Celia Regina da Silva Garcia
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14. Ca(v)1.3 and deafness
- Dr. Amy Lee
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16. Vascular calcification location, formation and biological activity
- Dr. Diane Proudfoot
- Archived Lectures *These may not cover the latest advances in the field
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17. Ca2+ channelopathies
- Dr. David Friel
Printable Handouts
Navigable Slide Index
- Introduction
- Main actors in Ca2+ homeostasis mechanism
- Calcium signalling: dynamics and homeostasis
- Genetic disorders of Ca2+ channels and pumps (1)
- Events involved in a muscle twitch
- Membrane potential vs. time
- Neuro-muscular junction
- Multimolecular calcium signalling complexes
- Arrangement of proteins in SR and T tubule
- Sarcoplasmic reticulum
- Malignant hyperthermia
- Central core disease (CCD)
- Brody disease
- Organisation of cardiac calcium signalling
- Arrithmogenic right ventricular dysplasia 2-ARVD2
- Genetic disorders of Ca2+ channels and pumps (2)
- Structure of voltage-gated Ca2+ channels
- Familial hemiplegic migraine (FHM)
- Golgi can also be a Ca2+ storage compartment
- Hailey Hailey disease
- Mutation in Orai1 causes immune deficiency
- Summary
Topics Covered
- General concepts of calcium signaling
- Mechanisms of calcium extrusion/uptake
- Mechanisms of calcium release from the ER/SR
- General concepts about plasma membrane calcium channels
- Genetic defects of calcium release channels
- Genetic defects of plasma membrane calcium channels
- Genetic defects of calcium pumps
- Novel findings on genetic defects of store dependent calcium channels
Talk Citation
Pozzan, T. (2007, October 1). Genetic defects and calcium [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 18, 2024, from https://hstalks.com/bs/428/.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Tullio Pozzan has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.