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- 2023
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1. Planning and response to COVID-19: lessons from China and South-East Asia
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2. The emergence of the SARS-CoV-2 Omicron variant
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3. How is Omicron different?
- Prof. Emma Thomson
- 2021
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5. Potential of ‘long-COVID’ in triggering chronic co-pathologies
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6. SARS-CoV-2 monoclonal antibody testing in vivo
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7. mRNA COVID-19 vaccine efficacy in recovered vs COVID-naive individuals
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8. SARS-CoV-2 variants: implications for immunity and vaccine development
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10. SARS-COV-2 human monoclonal antibody therapy update
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11. Emergence of blood clotting disorders resulting from COVID vaccines inoculations
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12. SARS-CoV-2 evolution within and between individuals
- Prof. Katia Koelle
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13. Identifying SARS-CoV-2 proteases
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14. Genetic surveillance and the emergence of SARS-CoV-2 variants
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15. The COVID-19 outbreak: April 2021 update
- Prof. Jonathan Temte
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16. ABO blood groups and SARS-CoV-2 susceptibility
- Dr. Sean Stowell
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17. Impact of COVID-19 on neuropsychiatric disorders and mental health
- Prof. Anthony David
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18. The immune system response to the SARS-CoV-2 virus: March 2021 update
- Prof. Paul Klenerman
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23. SARS-CoV-2 vaccine rollout campaigns
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25. Interspecies transmission of SARS-CoV-2
- Dr. Dalan Bailey
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26. Complement activation in COVID-19
- Prof. Jeffrey Laurence
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27. Human movement patterns and local spread of COVID-19
- Prof. Ben Cowling
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28. SARS-CoV-2 mutations: phenotypes and implications for vaccine development
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29. The immune system response to the SARS-CoV-2 virus: December 2020 update
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30. Triage and end of life care planning in COVID-19
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31. Natural killer cells as COVID-19 therapy
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32. Update on the SNG001 drug, an INFβ therapy for COVID-19
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34. Identification of a new coronavirus-specific RNA export protein complex
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35. The neurological symptoms of COVID-19
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36. Imperial College London’s saRNA Vaccine - COVAC1
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37. Interferon-α2b as a therapy for COVID-19
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38. Potential long-term health effects of a SARS-CoV-2 infection
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39. The COVID-19 coronavirus outbreak: October 2020 update
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41. Rheumatic diseases and COVID-19
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42. The cardiovascular complications of SARS-CoV-2 infection
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43. Medical wearable devices for tracking symptoms of COVID-19
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44. Risk of re-emergence of COVID-19 after exit from lockdown
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45. The evolutionary origin of SARS-CoV-2
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46. Predicting COVID-19 outbreaks by measuring SARS-CoV-2 RNA in sewage sludge
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47. Approaches for elucidating genetic susceptibility to SARS-CoV-2
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48. The immune system response to the SARS-CoV-2 virus: July 2020 update
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49. The impact of COVID-19 in the elderly and in care homes
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50. Human challenge trials for vaccines against COVID-19
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51. The development of SARS-CoV-2 vaccines
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52. Convalescent plasma therapy as a treatment for COVID-19
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53. Remdesivir COVID-19 clinical trial
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54. Nanotechnologies in the fight against coronaviruses
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55. The COVID-19 coronavirus outbreak: May 2020 update
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56. INFβ therapy for COVID-19: the new SNG001 drug
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57. Strategies for exiting the lockdown
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58. SARS-CoV-2 human monoclonal antibody therapy
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59. An FDA approved salivary test for SARS-CoV-2 infection
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60. Development of an intranasal vaccine for SARS-CoV-2
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61. The immune system response to the SARS-CoV-2 virus: an update
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62. A novel AIOD-CRISPR system for diagnosis of SARS-CoV-2
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63. Development of PRO-140 (Leronlimab) as a treatment for COVID-19
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64. COVID-19 epidemiology and potential treatments: follow up interview
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65. SARS-CoV-2 vaccine development: where are we now?
- Prof. Gary Kobinger
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66. SARS-CoV-2: What we need to know and possible future therapies
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67. SARS-CoV-2 vaccine: current biological targets and considerations
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68. The current understanding of the biology of the SARS-CoV-2 virus
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70. The immune system response to the SARS-CoV-2 virus
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71. SARS-CoV-2 vaccine development
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72. The COVID-19 outbreak: an update on the SARS-CoV-2 virus
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73. The COVID-19 coronavirus outbreak: a current view
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74. The COVID-19 coronavirus outbreak: March 2020 update
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Topics Covered
- Vaccine development for SARS-COV-2: Current position
- Different types of potential vaccines against COVID-19
- New technologies and their implications
- How past experience can support current research
Biography
Gary Kobinger is a Professor in the Department of Microbiology and Infectious Diseases and the Director of the Research Centre on Infectious Diseases, Faculty of Medicine at Université Laval. He is also an adjunct Professor in the Department of Pathology and Laboratory Medicine at the University of Pennsylvania, and an Associate Professor in the Department of Medical Microbiology at the University of Manitoba.
His work focuses on developing and testing new vaccine platforms and immune treatments against emerging and re-emerging viruses of high consequences to public health.
Links
Series:
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Talk Citation
Kobinger, G. (2020, April 6). SARS-CoV-2 vaccine development: where are we now? [Audio file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 20, 2024, from https://hstalks.com/bs/4238/.Export Citation (RIS)
Publication History
Financial Disclosures
- Consultant of Inovio Inc for their program on Lassa DNA vaccine development (not mentioned in the talk but the DNA platform for Zika is included and Inovio is on 2 of the slides to acknowledge their contribution). I have not received financial compensation yet however it is possible that I will this year or next to a maximum of $5000 USD/year.
A selection of talks on Vaccines
Transcript
Please wait while the transcript is being prepared...
0:00
Interviewer: Professor Kobinger,
thank you very much for
taking the time today to record this
interview about where we currently stand
in the development of a vaccine for
the SARS-CoV-2 virus.
Could you firstly give us an overview
of where we currently stand on vaccine
development?
Prof. Kobinger: Yes, the overview on
vaccine development is not that easy in
the sense that I'm one person, I don't
know everything in the field in real time.
That being said, I know a fair amount and
I will share this with you.
We're seeing a lot of
different possibilities,
we use the words 'vaccine platforms'
which means different vaccines or
vaccine strategies, it could be the same
vaccine but for example, with or
without adjuvants or different regimens
(say one, two or three doses).
What's happening right now in terms of a
high-level overview: there is one vaccine
based on RNA that entered clinical trials
last week or two weeks ago in the US,
there is another vaccine based on DNA
set to enter clinical trials this month,
which is pending approval
from the FDA (the Food and
Drug Administration),
so it's their decision.
They could say 'not this Monday but
the following one',
from what I'm hearing it should
start before the end of April.
There is a lot of effort,
notably in Europe from CEPI,
that is funding many different
vaccines and vaccine strategies.
The DNA vaccine that I just
talked about is one of them, but
there are more: Johnson & Johnson
also has a vaccine that is advancing,
they said publicly yesterday (or
the day before) that they were going