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1. Introduction
2. Mitochondria & early embryogenesis
3. mtDNA content of the embryo
4. Embryo & activation of mitochondrial biogenesis
5. Embryogenesis defect & mitochondrial biogenesis
6. Embryogenesis defect & mitochondrial dynamics
7. Mitochondria & embryonic physiology
8. Mitochondrial DNA during early embryogenesis
9. Energetic needs and redox status of the embryo
10. Changes in mitochondrial structure & function
11. Mitochondrial activation
12. Mitochondria & embryonic differentiation
13. Oocyte and cumulus cells interactions
14. Cumulus cells and oocyte mtDNA pool
15. Variables linked to oocyte mitochondrial mass
16. mtDNA quantification: marker of embryonic quality
17. Haplogroups and fertility (bovine)
18. Haplogroups & ovarian reserve (human)
19. Haplogroup JT and markers of ovarian reserve
20. Oocyte competence & mitochondrial manipulations
21. Cytoplasm donation
22. The “3 parent” technique
23. Extending the indications
24. Potential risks
25. Augmenting mitochondrial mass & function
26. Conclusions
27. Acknowledgements
28. Bibliography (1)
29. Bibliography (2)
30. Bibliography (3)
31. Bibliography (4)
32. Bibliography (5)
33. Bibliography (6)
34. Bibliography (7)
35. Bibliography (8)
36. Bibliography (9)

Topics Covered

• Mitochondria and embryogenesis
• Mitochondria and ovarian ageing
• The role of cumulus granulosa cells
• Mitochondrial genetics and fertility
• Targeting mitochondria to improve oocyte quality

Links

Series:

• Mitochondrial Biogenesis

Categories:

• Biochemistry
• Clinical Medicine
• Diseases, Disorders, & Treatments
• Genetics & Epigenetics
• Reproduction & Development

Therapeutic Areas:

• Gynaecology & Obstetrics

Talk Citation

Panloup, P.M. (2018, September 27). Mitochondria in reproduction and fertility: mitochondria and embryo 2 [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 18, 2018, from https://hstalks.com/bs/3818/.

Talk Information

• Published on September 27, 2018