An introduction to the world of microbes
40 min
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- General Virology
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46 min
1. Principles of virology- Prof. Vincent Racaniello
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36 min
2. Antiviral drugs (non-HIV)- Prof. Megan Shaw
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36 min
3. The type I interferon system and viruses- Dr. Adolfo Garcia-Sastre
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45 min
4. Immune responses to viruses- Prof. Paul Klenerman
- Emerging Pathogens
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29 min
5. Emerging or newly discovered viral causes of acute lower respiratory tract infections worldwide- Dr. Marietjie Venter
- Mrs. Orienka Hellferscee
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37 min
6. Emerging respiratory viruses - discoveries between 2001 and 2005- Prof. Ron Fouchier
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28 min
7. Usage of vaccines and therapeutics in public health emergencies 1- Prof. Gary Kobinger
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39 min
8. Usage of vaccines and therapeutics in public health emergencies 2- Prof. Gary Kobinger
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50 min
9. Influenza virus pandemics: past and future- Prof. Peter Palese
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63 min
10. SARS-CoV and other emerging coronaviruses- Prof. Ralph Baric
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36 min
11. Dengue, Zika and Chickungunya viruses- Prof. Ana Fernandez-Sesma
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41 min
12. Biodefense challenges- Dr. David Franz
- Important Pathogens and their Diseases
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38 min
13. Natural history and pathogenesis of herpes virus infections- Prof. Richard Whitley
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40 min
14. Cytomegalovirus biology- Prof. Domenico Tortorella
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46 min
15. Hepatitis C virus: discovery, cure and protection- Dr. Matthew Evans
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32 min
16. Fundamentals of HIV biology- Prof. Viviana Simon
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44 min
17. Measles- Prof. Diane E. Griffin
- New Frontiers
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45 min
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55 min
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30 min
20. Viruses as anticancer weapons- Prof. Roberto Cattaneo
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48 min
21. Novel approaches to diagnosis of viral infections- Prof. W. Ian Lipkin
- Archived Lectures *These may not cover the latest advances in the field
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43 min
22. Principles of virology I- Prof. Richard Condit
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43 min
23. Principles of virology II- Prof. Richard Condit
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36 min
24. Complex DNA viruses: herpes virus- Dr. John Blaho
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38 min
25. Adeno-associated viruses (AAV)- Prof. Kenneth Berns
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60 min
26. Poxviruses: smallpox (variola), vaccinia and monkeypox- Prof. Paula Traktman
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26 min
27. Can HPV testing be the sole primary cervical screening modality?- Prof. Jack Cuzick
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29 min
28. From viruses to oncolytics- Prof. Roberto Cattaneo
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38 min
29. Non HIV antivirals- Prof. Mary Klotman
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42 min
30. Gastroenteritis viruses- Prof. Mary Estes
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46 min
31. Biodefense challenges- Dr. Connie Schmaljohn
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32 min
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49 min
33. The past, present and future of vaccination- Prof. Stanley Plotkin
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41 min
34. Filoviruses- Dr. Christopher Basler
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41 min
35. Bunyaviruses- Prof. Richard Elliott
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41 min
36. The immunobiology of HIV- Prof. Norman Letvin
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59 min
37. Hepatitis C and HCV- Prof. Stanley Lemon
Printable Handouts
Navigable Slide Index
- Introduction
- Nucleoside analogues: first line herpes antivirals
- Phosphorylation of acyclic nucleoside analogues
- Acyclovir (zovirax)
- Mechanism of action of acyclovir
- Pharmacokinetics of acyclovir and valacyclovir
- Toxicities of acyclovir and valacyclovir
- Antiviral resistance
- Clinical application of acyclovir
- Clinical application continued
- Herpes gingivostomatitis/labialis
- First episode or recurrent genital herpes
- Severe HSV disease: IV high-dose acyclovir
- Varicella zoster
- Other anti-HSV drugs
- Anti-CMV drugs: ganciclovir and valganciclovir
- Mechanism and pharmacokinetics of ganciclovir
- Toxicities of ganciclovir
- Ganciclovir resistance
- Clinical indications for ganciclovir
- CMV retinitis in AIDS
- Alternative anti-herpes drugs: foscarnet (foscavir)
- Foscarnet: pharmacokinetics and toxicities
- Foscarnet: resistance and clinical indications
- Cidofovir (vistide)
- Cidofovir: pharmacokinetics and toxicities
- Cidofovir: clinical indications and resistance
- Fomivirsen (vitravene)
- Influenza: orthmyxoviridae family
- Antiviral targets in influenza
- Anti-viral drugs for prevention/treatment of influenza
- Anti-influenza drugs: M2 inhibitors (1)
- Anti-influenza drugs: M2 inhibitors (2)
- Anti-influenza drugs: neuraminidase inhibitors
- Oseltamivir pharmacokinetics and toxicities
- Oseltamivir: clinical indications
- Oseltamivir vs. placebo in normal adults
- Time to symptom resolution in flu-infected patients
- Six week prevention trial: community flu outbreak
- Anti-hepatitis B drugs
- Lamivudine for HBV - toxicities and resistance
- Lamivudine for hepatitis B - clinical indications
- Adefovir dipivoxil (hepsera)
- Adefovir dipivoxil - pharmacokinetics, resistance
- Adefovir dipivoxil (hepsera) - clinical indications
- Entecavir: hepatitis B antiviral
- Entecavir continued...
- Resistance rates: lamivudine, hepsera, entecavir
- Recombinant interferon alpha
- Recombinant interferon
- Recombinant interferon - clinical indications (1)
- Recombinant interferon - clinical indications (2)
- Ribavirin: role in HCV infection
- Ribavirin
- Conclusions
Topics Covered
- Pharmacokinetics and clinical application of antiviral agents excluding antiretrovirals for HIV
- The therapeutic and prophylactic options for herpes infections including herpes simplex 1 and 2, varicella zoster and cytomegalovirus
- Therapeutic and prophylactic agents for influenza
- Approved agents for the treatment of hepatitis B and C
Links
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Talk Citation
Klotman, M. (2007, October 1). Non HIV antivirals [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 3, 2023, from https://hstalks.com/bs/355/.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Mary Klotman has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
