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- General Virology
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1. Principles of virology
- Prof. Vincent Racaniello
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2. Antiviral drugs (non-HIV)
- Prof. Megan Shaw
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3. The type I interferon system and viruses
- Dr. Adolfo Garcia-Sastre
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4. Immune responses to viruses
- Prof. Paul Klenerman
- Emerging Pathogens
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5. Emerging or newly discovered viral causes of acute lower respiratory tract infections worldwide
- Dr. Marietjie Venter
- Mrs. Orienka Hellferscee
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6. Emerging respiratory viruses - discoveries between 2001 and 2005
- Prof. Ron Fouchier
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7. Usage of vaccines and therapeutics in public health emergencies 1
- Prof. Gary Kobinger
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8. Usage of vaccines and therapeutics in public health emergencies 2
- Prof. Gary Kobinger
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9. Influenza virus pandemics: past and future
- Prof. Peter Palese
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10. SARS-CoV and other emerging coronaviruses
- Prof. Ralph Baric
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11. Dengue, Zika and Chickungunya viruses
- Prof. Ana Fernandez-Sesma
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12. Biodefense challenges
- Dr. David Franz
- Important Pathogens and their Diseases
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13. Natural history and pathogenesis of herpes virus infections
- Prof. Richard Whitley
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14. Cytomegalovirus biology
- Prof. Domenico Tortorella
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15. Hepatitis C virus: discovery, cure and protection
- Dr. Matthew Evans
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16. Fundamentals of HIV biology
- Prof. Viviana Simon
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17. Measles
- Prof. Diane E. Griffin
- New Frontiers
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20. Viruses as anticancer weapons
- Prof. Roberto Cattaneo
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21. Novel approaches to diagnosis of viral infections
- Prof. W. Ian Lipkin
- Archived Lectures *These may not cover the latest advances in the field
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22. Principles of virology I
- Prof. Richard Condit
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23. Principles of virology II
- Prof. Richard Condit
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24. Complex DNA viruses: herpes virus
- Dr. John Blaho
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25. Adeno-associated viruses (AAV)
- Prof. Kenneth Berns
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26. Poxviruses: smallpox (variola), vaccinia and monkeypox
- Prof. Paula Traktman
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27. Can HPV testing be the sole primary cervical screening modality?
- Prof. Jack Cuzick
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28. From viruses to oncolytics
- Prof. Roberto Cattaneo
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29. Non HIV antivirals
- Prof. Mary Klotman
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30. Gastroenteritis viruses
- Prof. Mary Estes
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31. Biodefense challenges
- Dr. Connie Schmaljohn
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33. The past, present and future of vaccination
- Prof. Stanley Plotkin
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34. Filoviruses
- Dr. Christopher Basler
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35. Bunyaviruses
- Prof. Richard Elliott
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36. The immunobiology of HIV
- Prof. Norman Letvin
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37. Hepatitis C and HCV
- Prof. Stanley Lemon
Printable Handouts
Navigable Slide Index
- Introduction
- Nucleoside analogues: first line herpes antivirals
- Phosphorylation of acyclic nucleoside analogues
- Acyclovir (zovirax)
- Mechanism of action of acyclovir
- Pharmacokinetics of acyclovir and valacyclovir
- Toxicities of acyclovir and valacyclovir
- Antiviral resistance
- Clinical application of acyclovir
- Clinical application continued
- Herpes gingivostomatitis/labialis
- First episode or recurrent genital herpes
- Severe HSV disease: IV high-dose acyclovir
- Varicella zoster
- Other anti-HSV drugs
- Anti-CMV drugs: ganciclovir and valganciclovir
- Mechanism and pharmacokinetics of ganciclovir
- Toxicities of ganciclovir
- Ganciclovir resistance
- Clinical indications for ganciclovir
- CMV retinitis in AIDS
- Alternative anti-herpes drugs: foscarnet (foscavir)
- Foscarnet: pharmacokinetics and toxicities
- Foscarnet: resistance and clinical indications
- Cidofovir (vistide)
- Cidofovir: pharmacokinetics and toxicities
- Cidofovir: clinical indications and resistance
- Fomivirsen (vitravene)
- Influenza: orthmyxoviridae family
- Antiviral targets in influenza
- Anti-viral drugs for prevention/treatment of influenza
- Anti-influenza drugs: M2 inhibitors (1)
- Anti-influenza drugs: M2 inhibitors (2)
- Anti-influenza drugs: neuraminidase inhibitors
- Oseltamivir pharmacokinetics and toxicities
- Oseltamivir: clinical indications
- Oseltamivir vs. placebo in normal adults
- Time to symptom resolution in flu-infected patients
- Six week prevention trial: community flu outbreak
- Anti-hepatitis B drugs
- Lamivudine for HBV - toxicities and resistance
- Lamivudine for hepatitis B - clinical indications
- Adefovir dipivoxil (hepsera)
- Adefovir dipivoxil - pharmacokinetics, resistance
- Adefovir dipivoxil (hepsera) - clinical indications
- Entecavir: hepatitis B antiviral
- Entecavir continued...
- Resistance rates: lamivudine, hepsera, entecavir
- Recombinant interferon alpha
- Recombinant interferon
- Recombinant interferon - clinical indications (1)
- Recombinant interferon - clinical indications (2)
- Ribavirin: role in HCV infection
- Ribavirin
- Conclusions
Topics Covered
- Pharmacokinetics and clinical application of antiviral agents excluding antiretrovirals for HIV
- The therapeutic and prophylactic options for herpes infections including herpes simplex 1 and 2, varicella zoster and cytomegalovirus
- Therapeutic and prophylactic agents for influenza
- Approved agents for the treatment of hepatitis B and C
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Klotman, M. (2007, October 1). Non HIV antivirals [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 2, 2023, from https://hstalks.com/bs/355/.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Mary Klotman has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.