JOSHUA SHIFFMAN: Hello.
My name is Joshua Shiffman.
I am a pediatric oncologist
at the University of Utah,
where I take care of patients
with hereditary cancer syndromes
as well as do research in the field.
Today, we're going to talk about
the importance of family history.
We will cover several of the more
common hereditary cancer syndromes
including, GI cancers, breast
cancers, Li-Fraumeni Syndrome,
Paraganglioma and VHL syndromes.
And finally, we'll end with some
brief discussion about research
in the field of hereditary
related to comparative oncology.
Cancer is quite common.
In fact, it is one of the leading
causes of death around the world,
and 15 people will die
from cancer every minute.
Half of all men and
a third of all women
will develop cancer
throughout their lifetime.
This makes the study of
cancer and the risk for cancer
quite relative to disease
and impact on human health.
In terms of the genetic
risk for cancer,
we believe that as
many as 1 in 10 adults
will have cancer that is caused
to an inherited genetic risk.
This comes to approximately
160,000 new diagnoses per year
for cancer in the US alone.
In terms of childhood
cancer, we believe
that it may be as
high as 1 in 3 children
who have developed cancer
due to an inherited genetic risk.
This comes to approximately 4,500
new diagnoses for cancer per year.