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- Human Population Genetics: An Overview
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1. Modern human origins
- Prof. Richard Klein
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2. History and geography of human genetic diversity I
- Prof. Luigi Luca Cavalli-Sforza
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3. History and geography of human genetic diversity II
- Prof. Luigi Luca Cavalli-Sforza
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4. Cultural evolution
- Prof. Marcus Feldman
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5. The human genomes
- Prof. Gil McVean
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6. Human population structure
- Prof. Noah Rosenberg
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7. The signature of local adaptations in human polymorphism data
- Dr. Anna Di Rienzo
- The Human Genome Project
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8. The HapMap project
- Prof. Andrew Clark
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9. Major gene families in humans and their evolutionary history
- Prof. Yoshihito Niimura
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10. Evolution of human mitochondrial DNA variations
- Prof. Toomas Kivisild
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11. Ethical issues in human population genetics
- Prof. Henry Greely
- Important Phenotypic Phenomena
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12. Evolution: how genes and their variation got here
- Prof. Kenneth Weiss
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13. The genetic component to diabetes
- Dr. Nancy Cox
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14. Genetics of breast and ovarian cancer
- Prof. Jeffrey Weitzel
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15. Colorectal cancer and the rare variant hypothesis
- Prof. Sir Walter Bodmer
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16. Genetic diseases in the Jewish population
- Prof. Neil Risch
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17. The genetics of French Canadians
- Dr. Bernard Brais
- Dr. Bertrand Desjardins
- Prof. Damian Labuda
- Dr. Marc St-Hilaire
- Prof. Marc Tremblay
- Prof. Helene Vezina
- Historical and Geographical Genetic Variation
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18. Human genetic variation of Africa
- Prof. Joanna Mountain
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19. Genetics of Pakistani populations in an Asian and global context
- Prof. S. Qasim Mehdi
- Archived Lectures *These may not cover the latest advances in the field
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20. The genetics of breast and ovarian cancer
- Dr. Piri Welcsh
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21. Historical and geographical genetic variation: Europe
- Prof. Antonio Torroni
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22. Linguistic evolution
- Dr. Merritt Ruhlen
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23. Human microsatellite and minisatellite DNA polymorphisms
- Dr. James Weber
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24. Human population genetics: lifespan
- Prof. Kaare Christensen
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25. History and geography of human genetic diversity III
- Prof. Luigi Luca Cavalli-Sforza
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26. Major gene families in humans and their evolutionary history
- Prof. Yoshihito Niimura
- Prof. Masatoshi Nei
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27. Natural selection and sequence polymorphism
- Prof. Austin Hughes
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28. Human Y chromosome phylogenetics and phylogeography
- Prof. Peter Underhill
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29. The peopling of the Americas: new insights from genetic studies
- Dr. Theodore Schurr
Printable Handouts
Navigable Slide Index
- Introduction
- Human lifespan - a heritable trait?
- Human lifespan - a phenotype of vital importance
- Lecture outline
- Changes in human lifespan during the 20th century
- Female life expectancy in the 20th century
- Mortality reductions since 1950
- Record life-expectancy
- Germany 1980-2000 (1)
- Germany 1980-2000 (2)
- Germany 1980-2000 (3)
- Lifespan - a plastic trait
- Large variation in lifespan within a birth cohort
- Chance
- Lifespan C. elegans
- Lifespan - summary
- Lifespan phenotypes
- Genetic epidemiology of lifespan
- Family aggregation
- Family data
- Twin studies
- Twin lifespan
- The individual level of twin studies (1)
- The individual level of twin studies (2)
- The individual level of twin studies (3)
- Human co-twin lifespan
- Twin design
- Genetic influence on human lifespan and longevity
- Danish twin cohorts
- Swedish twin cohorts
- Finnish twin cohorts
- Number of twin pairs
- Twin-twin plot
- Relative recurrence risk
- Lifespan of twin by lifespan of co-twin
- Change in lifespan of twin by lifespan of co-twin
- Conclusion
- The genetic architecture of human longevity
- Genetic study design in longevity research
- What has been found so far?
- The frequencies of ApoE alleles vary with age
- Molecular pathways that lengthen lifespan
- Other good candidates
- Guidelines for future studies
- Collaborators
Topics Covered
- Human lifespan as a heritable trait
- Lifespan phenotypes
- Genetic epidemiology of human lifespan
- The genetic architecture of human longevity
- Genetic study designs in longevity research
Talk Citation
Christensen, K. (2007, October 1). Human population genetics: lifespan [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved March 28, 2024, from https://hstalks.com/bs/317/.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Kaare Christensen has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.