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- Human Population Genetics: An Overview
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1. Modern human origins
- Prof. Richard Klein
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2. History and geography of human genetic diversity I
- Prof. Luigi Luca Cavalli-Sforza
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3. History and geography of human genetic diversity II
- Prof. Luigi Luca Cavalli-Sforza
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4. Cultural evolution
- Prof. Marcus Feldman
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5. The human genomes
- Prof. Gil McVean
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6. Human population structure
- Prof. Noah Rosenberg
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7. The signature of local adaptations in human polymorphism data
- Dr. Anna Di Rienzo
- The Human Genome Project
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8. The HapMap project
- Prof. Andrew Clark
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9. Major gene families in humans and their evolutionary history
- Prof. Yoshihito Niimura
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10. Evolution of human mitochondrial DNA variations
- Prof. Toomas Kivisild
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11. Ethical issues in human population genetics
- Prof. Henry Greely
- Important Phenotypic Phenomena
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12. Evolution: how genes and their variation got here
- Prof. Kenneth Weiss
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13. The genetic component to diabetes
- Dr. Nancy Cox
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14. Genetics of breast and ovarian cancer
- Prof. Jeffrey Weitzel
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15. Colorectal cancer and the rare variant hypothesis
- Prof. Sir Walter Bodmer
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16. Genetic diseases in the Jewish population
- Prof. Neil Risch
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17. The genetics of French Canadians
- Dr. Bernard Brais
- Dr. Bertrand Desjardins
- Prof. Damian Labuda
- Dr. Marc St-Hilaire
- Prof. Marc Tremblay
- Prof. Helene Vezina
- Historical and Geographical Genetic Variation
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18. Human genetic variation of Africa
- Prof. Joanna Mountain
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19. Genetics of Pakistani populations in an Asian and global context
- Prof. S. Qasim Mehdi
- Archived Lectures *These may not cover the latest advances in the field
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20. The genetics of breast and ovarian cancer
- Dr. Piri Welcsh
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21. Historical and geographical genetic variation: Europe
- Prof. Antonio Torroni
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22. Linguistic evolution
- Dr. Merritt Ruhlen
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23. Human microsatellite and minisatellite DNA polymorphisms
- Dr. James Weber
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24. Human population genetics: lifespan
- Prof. Kaare Christensen
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25. History and geography of human genetic diversity III
- Prof. Luigi Luca Cavalli-Sforza
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26. Major gene families in humans and their evolutionary history
- Prof. Yoshihito Niimura
- Prof. Masatoshi Nei
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27. Natural selection and sequence polymorphism
- Prof. Austin Hughes
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28. Human Y chromosome phylogenetics and phylogeography
- Prof. Peter Underhill
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29. The peopling of the Americas: new insights from genetic studies
- Dr. Theodore Schurr
Printable Handouts
Navigable Slide Index
- Introduction
- Genetic markers inherited from a single parent
- NRY and mtDNA form genealogies
- Most recent common ancestor (MRCA)
- Mutation rates
- Mutational history of the Y chromosome (NRY)
- Human NRY chromosome phylogeny explanation
- The phylogeny
- NRY and mitochondria genealogies are similar
- NRY - Stanford University
- mtDNA - Stanford University
- Of Adam and Eve
- All Y chromosomes descend from one male
- How many humans lived at the time?
- Why didn't Adam and Eve live at the same time?
- Primates, genus Homo, species sapiens
- Transition to bipedality
- Bipedality freed hands for making tools
- Growth and expansion to the Old World
- Spread of modern humans from East Africa (1)
- Spread of modern humans from East Africa (2)
- Spread of modern humans from East Africa (3)
- Spread of humans according to Y chromosome
- Map of likely expansion of the Y chromosome
- Areas of origin of agriculture and animal breeding
- Agriculture and animal breeding development areas
- Spread of cultivated wheat to Europe
- The map of spread of cultivated wheat to Europe
- Geographic maps of major migrations in Europe
- The scale of principal components (1)
- The scale of principal components (2)
- The first principal component
- Agricultural diffusion - 1/3 demic and 2/3 cultural
- The second principal component
- The second principal component - map
- The third principal component
- The third principal component - map
- Commensal coevolution and hitchiking: H. pylori
- Similarities of humans and bacteria
- Similar clinal gradients of H. pylori and humans
- Coevolution of humans and cattle
- The migration of Scandinavians to Iceland
- Genetic distances between cattle of different origin
- Etruscans
- Summary
Topics Covered
- Genetic markers inherited from a single parent
- Mutational history of the Y chromosome (NRY)
- Genealogies of Y chromosome and mitochondria
- Of Adam and Eve
- Primates and Homo sapiens
- Neanderthal and the spread of modern humans from East Africa
- The spread of modern humans according to Y chromosome
- Areas of origin of agriculture and animal breeding
- Spread of cultivated wheat to Europe in the Neolithic period
- Geographic maps of the first three principal components of Europe
- Coevolution and hitchhiking of commensals: Helicobacter pylori
- Coevolution of humans and cattle
Talk Citation
Cavalli-Sforza, L.L. (2007, October 1). History and geography of human genetic diversity II [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 24, 2024, from https://hstalks.com/bs/302/.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Luigi Luca Cavalli-Sforza has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
History and geography of human genetic diversity II
Published on October 1, 2007
40 min