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• 45 min
  1. Molecular and cellular regulation of wound healing; what goes wrong when wounds fail to heal or heal too much?

  • Prof. Gregory Schultz
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  • Prof. Chandan K. Sen
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  3. Genes in skin wound healing: microRNAs 2

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• 46 min
  4. Biofilms and chronic wounds: winning the war in wounds

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  5. Dynamic reciprocity and wound healing

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• 66 min
  6. Wound bed preparation and TIME

  • Prof. David Leaper
• 32 min
  7. Negative pressure wound therapy: mechanisms of action and clinical uses

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• 48 min
  8. Deep tissue injury: the state of the science

  • Prof. Joyce Black
• 42 min
  9. Biofilm based wound care

  • Dr. Randall Wolcott
• 42 min
  10. Understanding poor lymphatic function and how to improve it: revisiting old facts and examining new leads to help wounds heal

  • Prof. Neil Piller
• 24 min
  11. Hidradenitis suppurativa: current understanding and management

  • Dr. John W. Frew

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Lymphoedema and oedema - key differences
3. Importance of understanding the lymphatic system
4. Blood-tissue-lymph systems and their interfaces
5. Lymphatics is a sewerage system
6. Importance of the lymphatic system
7. Organization of superficial lymph system
8. Functioning of the lymphatic system
9. Lymphangions visualization
10. Initial lymphatics
11. Key practical points - lymphatics
12. Detailed functioning of the lymphatic system
13. Lymph nodes
14. Key practical point - lymph nodes
15. Big picture overview
16. Lymph as an environment
17. Key practical point - lymph environment
18. Deep and superficial systems
19. The deep lymphatic system in torso
20. Key practical point - deep/superficial systems
21. The adipo-lymphatic connection
22. Fats in the diet & lymph load and flow
23. Lymphatic drainage from the small intestine
24. Chylous reflux into limbs, urinary and genital areas
25. Key practical point - diet and the lymphatics
26. Factors which determine lymph load
27. Factors which determine lymph flow
28. Development of lymphoedema
29. Types of lymphoedemas
30. Primary lymphoedema
31. Genetics of primary lymphoedema
32. Secondary lymphoedema
33. Pre-disposition to lymphoedema
34. The three stages of lymphoedema
35. Lymphoedema - one developmental view
36. Each territory may be affected differently
37. Fatty epi-fascial tissue accumulation
38. Subcutaneous fat and lymph transport
39. Lymphoedema is more than just a swelling!
40. Skin changes in lymoedema
41. Buildup of fibrous tissues consequences
42. The problems of fibrosis
43. Key practical point - fibrous build up
44. Proximity issues
45. Proximity issues - lymph and vascular systems
46. Lymphatics in adventitial areas of veins
47. Proximity issues - diseases and disorders
48. Key practical point - proximity issues
49. Conditions which look like lymphoedema
50. Lipoedemas
51. Development of lipoedema
52. Basic pathology
53. Myxoedema
54. Phlebo-lymphoedema
55. Development phlebo-lymphoedema
56. Key practical point - look alike conditions
57. Back to lymphoedema
58. Adipose tissue, fibrosis and lymphoedema
59. Key practical point - adipose tissues & fibrosis
60. Remember the differences?
61. What should we do to improve tissue/cell health?

Topics Covered

• Lymphoedema and oedema: key differences
• Blood-tissue-lymph systems and their interfaces
• Importance of the lymphatic system
• Organization of superficial lymph system
• Functioning of the lymphatic system
• Consequences of poor lymph flow
• Deep and superficial systems
• The adipo-lymphatic connection
• Fats in the diet: How they affect lymph flow and load
• Lymphatic drainage from the small intestine
• Blockage/overload and chylous reflux
• Factors which determine lymph load and flow
• Development of lymphoedema
• Types of lymphoedemas
• Increased subcutaneous fat reduces lymph transport
• Build-up of fibrous tissues reduces lymphatic function
• The problems of fibrosis
• Proximity issues
• Other limb swellings which look like lymphoedema which may underlie the wound area: Lipoedemas, Myxoedema and Phlebo-lymphoedema
• Adipose tissue, fibrosis and lymphoedema
• What can be done to improve tissue/cell health and improve wound healing?
• Update interview: Use of Indocyanine green to visual functional lymphatics
• Update interview: Use of objective measurements to ensure sequenced and targeted treatment
• Update interview: Importance of patient empowerment

Links

Series:

• Wound Healing

Categories:

• Clinical Practice
• Immunology
• Physiology & Anatomy

Therapeutic Areas:

• Cardiovascular & Metabolic
• Immunology & Inflammation
• Oncology

Talk Citation

Publication History

• Published on October 7, 2014
• Updated on July 10, 2023

Financial Disclosures

• Prof. Neil Piller has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.

Update Available

The speaker addresses developments since the publication of the original talk. We recommend listening to the associated update as well as the lecture.

1. Embed full lecture Full lecture Duration: 41:32 min Embed full lecture
2. Embed Update Interview Update Interview Duration: 11:38 min Embed Update Interview