TY - ADVS TI - Turning genomic junk into treasure: genetic engineering with the Sleeping Beauty transposon system AU - Ivics, Zoltan A2 - Naldini, Luigi PY - 2014 DA - 2014/08/05 UR - https://hstalks.com/bs/2876/ AB - Transposons can be viewed as natural DNA transfer vehicles, Transposons are capable of efficient genomic insertion, similar to integrating viruses, Transposition can be controlled by conditionally providing the transposase enzyme, DNA of interest cloned into a transposon-based vector can be utilized for stable genomic insertion in a regulated and highly efficient manner, Transposition opens up many avenues for genome manipulations in vertebrates, Generation of transgenic cells and germline-transgenic animals using transposons, The Sleeping Beauty synthetic transposon, Clinical applications of the Sleeping Beauty system DB - The Biomedical & Life Sciences Collection SN - 2056-452X ID - 3747 PB - Henry Stewart Talks ER -