Registration for a live webinar on 'Innovations in antibiotic discovery: combating resistant infections' is now open.
See webinar detailsWe noted you are experiencing viewing problems
-
Check with your IT department that JWPlatform, JWPlayer and Amazon AWS & CloudFront are not being blocked by your network. The relevant domains are *.jwplatform.com, *.jwpsrv.com, *.jwpcdn.com, jwpltx.com, jwpsrv.a.ssl.fastly.net, *.amazonaws.com and *.cloudfront.net. The relevant ports are 80 and 443.
-
Check the following talk links to see which ones work correctly:
Auto Mode
HTTP Progressive Download Send us your results from the above test links at access@hstalks.com and we will contact you with further advice on troubleshooting your viewing problems. -
No luck yet? More tips for troubleshooting viewing issues
-
Contact HST Support access@hstalks.com
-
Please review our troubleshooting guide for tips and advice on resolving your viewing problems.
-
For additional help, please don't hesitate to contact HST support access@hstalks.com
We hope you have enjoyed this limited-length demo
This is a limited length demo talk; you may
login or
review methods of
obtaining more access.
- Evolution of the Apoptotic Pathway
-
1. Apoptosis in C. elegans
- Prof. Michael Hengartner
- The Apoptotic Pathway in Humans
-
3. The death receptor signalling pathway
- Dr. Richard Siegel
-
4. Mitochondria and apoptosis
- Prof. Stephen Tait
- Apoptosis Molecules
-
5. The Bcl-2 family
- Dr. David Huang
-
6. Caspases
- Prof. Yuri Lazebnik
-
7. Natural caspase inhibitors
- Prof. Guy Salvesen
-
8. Mechanisms of apoptosis from structural biology
- Prof. Yigong Shi
- Clearance of Apoptotic Cells
-
10. Phagocytosis of apoptotic cells
- Prof. Peter Henson
- Non-Apoptotic Cell Death Programs
-
11. Autophagic cell death
- Prof. Eric Baehrecke
- Apoptosis and Disease
-
12. p53 and apoptosis
- Prof. Moshe Oren
-
13. The p53 family: function and molecular mechanisms
- Prof. Gerry Melino
-
14. Apoptosis in the immune system
- Prof. Peter Krammer
-
15. Apoptosis in the nervous system
- Prof. Pierluigi Nicotera
- Clinical Application of Apoptosis Research
-
16. Endothelial cell apoptosis
- Prof. Richard Kolesnick
-
17. Targeting apoptosis pathways in cancer therapy
- Dr. Simone Fulda
- Archived Lectures *These may not cover the latest advances in the field
-
18. Targeting apoptosis pathways in cancer therapy
- Dr. Irene Ghobrial
-
19. Apoptotic pathways in mammals
- Prof. Douglas Green
-
20. Lysosomal cell death pathways: new possibilities for cancer therapy
- Prof. Marja Jaattela
-
21. Degradation of apoptotic cells
- Prof. Shigekazu Nagata
-
22. Signaling during engulfment: the beginnings of a good meal
- Prof. Kodi Ravichandran
-
23. Apoptotic cell clearance deficiencies
- Prof. Martin Herrmann
-
24. Caspase inhibitors in drug discovery
- Dr. Tom O'Brien
-
25. Mitochondria in apoptosis
- Prof. Jean-Claude Martinou
Printable Handouts
Navigable Slide Index
- Introduction
- C.elegans is simple, yet sophisticated (1)
- C.elegans is simple, yet sophisticated (2)
- Nobel prize 02' was awarded to 3 worm workers (1)
- C.elegans hermaphrodite cell lineage
- Apoptosis in C.elegans (1)
- C.elegans embryonic development
- Time course of P11.aap death (Nomarski optics)
- Nobel prize 02' was awarded to 3 worm workers (2)
- C.elegans genetic programmed cell death
- C.elegans ced-3, ced-4 and ced-9 genes (1)
- Programmed cell death in the pharynx
- C.elegans ced-3, ced-4 and ced-9 genes ( 2)
- Activation of cell death machinery in C.elegans (1)
- Activation of cell death: C.elegans vs. mammals
- Mitochondria fragment during apoptosis
- Activation of cell death machinery in C.elegans (2)
- How does apoptosome activation regulated?
- Cell death activation via EGL-1 regulation
- Mutations in ces genes
- ces (cell death specification) genes
- ces genes mode of action model
- ces-1 and ces-2 encode transcription factors
- Conserved transcriptional regulation of apoptosis?
- Summary: apoptosis regulation in C.elegans
- Apoptosis in C.elegans ( 2)
- The adult C.elegans hermaphrodite germ cell line
- DNA damage induces germ cell apoptosis
- Radiation-induced germ cell apoptosis
- Effect of ced-9 (gf) or egl-1 (lf) on apopatosis (1)
- Transcriptional control of EGL-1 expression
- egl-1 mRNA levels increase following irradiation
- C.elegans p53 homolog: CEP-1
- A model for C.elegans DNA damage response (1)
- C.elegans checkpoint genes (1)
- A model for C.elegans DNA damage response (2)
- Simplified yeast DNA damage checkpoint pathway
- HUS1:GFP relocalizes to foci after DNA damage
- Hus1/rad-9 pathway is conserved through evolution
- A model for C.elegans DNA damage response (3)
- C.elegans checkpoint genes (2)
- C.elegans rad-5/clk-2 genes
- Summary: DNA damage response pathway
- The evolution of DNA damage response
- Effect of ced-9 (gf) or egl-1 (lf) on apopatosis (2)
- Effect of gla-3 (lf) on germ cell apoptosis
- GLA-3 is a candidate RNA-binding-protein
- GLA-3 interacts with MPK-1
- GLA-3 binds to effector docking site of MPK-1
- Ras-MAPK pathway is required to exit mitosis
- Ras-MAPK as a transient developmental stage
- EGF signaling pathway in C.elegans
- Genetic pathway for programmed cell death (1)
- Mutations in engulfment genes (1)
- Mutations in engulfment genes (2)
- Recognition and removal of apoptotic cells
- Genetic pathway for programmed cell death (2)
Topics Covered
- Programmed cell death in C. elegans during development and adulthood
- Differentiation
- The genetic pathway for programmed cell death
- ced-3, ced-4 and ced-9
- Activation of the cell death machinery during C. elegans development and in C. elegans vs. mammals
- How does C. elegans regulate activation of the apoptosome?
- Cell death specification (ces) genes
- NSM sister cell death
- Transcription factors
- A model for C. elegans DNA damage response
- gla-3
- A molecular model for the recognition and removal of apoptotic cells in C. elegans
Talk Citation
Hengartner, M. (2007, October 1). Apoptosis in C. elegans [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 28, 2025, from https://doi.org/10.69645/ZQAT2438.Export Citation (RIS)
Publication History
- Published on October 1, 2007
Financial Disclosures
- Prof. Michael Hengartner has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.