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Printable Handouts
Navigable Slide Index
- Introduction
- Talk outline
- Definition of severe asthma
- GINA 2006: asthma treatment steps (1)
- Evaluation of difficult asthma
- Alternative diagnoses for difficult-to-treat asthma
- Factors contributing to loss of control in asthma
- Asthma co-morbidities
- Definition of refractory asthma
- Severe asthma research program (SARP)
- SARP: demographics and treatments
- SARP: lung function & inflammatory markers
- GINA 2006: asthma treatment steps (2)
- Therapeutic approach: step 4
- Therapeutic approach: step 5
- Omalizumab on exacerbations in severe asthma
- Omalizumab in severe asthma: AQLQ
- Omalizumab for severe persistent allergic asthma
- Oral steroid-sparing agents
- Therapeutic approaches: the next 20 years
- Characteristics of severe asthma: heterogeneity
- Concept of phenotype
- SARP/NIH asthma cohort: cluster analysis (1)
- SARP/NIH asthma cohort: cluster analysis (2)
- Chronic airflow obstruction
- Severe asthma protocol
- Chronic airflow obstruction (1)
- Chronic airflow obstruction (2)
- Air-trapping in severe and non-severe asthma
- Air-trapping in severe asthma: SARP data
- Inflammatory & remodelling response in airways
- Submucosal biopsies in severe asthma
- Inflammatory cells in bronchial biopsies
- Induced sputum cells in severe asthma
- Sputum eosinophilic marker asthma analysis
- Airway wall remodelling in severe asthma
- HRCT and histology of airway
- Corticosteroid insensitivity in severe asthma
- Corticosteroid-dependent asthma
- Corticosteroid responsiveness
- Steroid-suppression of cytokine release
- Heterogeneity of 'causes' of CS insensitivity
- New treatments for severe asthma? (1)
- New treatments for severe asthma? (2)
- Mepolizumab in refractory eosinophilic asthma
- Effect of mepolizumab on exacerbations
- Treatment of severe asthma: summary
Topics Covered
- Definition and characterisation
- From difficult-to-treat asthma to severe asthma
- Phenotypes and characteristics
- Current treatment modalities
- Chronic airflow obstruction
- Corticosteroid insensitivity
- Future treatments: specific targets for specific phenotypes
Links
Series:
Categories:
- Biochemistry
- Cell Biology
- Clinical Medicine
- Diseases, Disorders & Treatments
- Immunology
- Pharmaceutical Sciences
Therapeutic Areas:
Talk Citation
Chung, F. (2012, December 27). Severe asthma: characterisation, mechanisms & treatment [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved January 24, 2021, from https://hstalks.com/bs/2461/.Publication History
Financial Disclosures
- Prof. Fan Chung has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Severe asthma: characterisation, mechanisms & treatment
Published on December 27, 2012
51 min