Topics Covered
- Introduction to the endoplasmic reticulum
- Protein folding and quality control within the endoplasmic reticulum
- Asn-linked glycosylation and oligosaccharide processing
- Calnexin and calreticulin
- Structure and functions
- The Calnexin cycle
- Recognition of substrate polypeptide by calnexin and calreticulin
- The dual binding model
- Role of ERp57 in glycoprotein folding by calnexin and calreticulin
- Peptidyl prolyl isomerases within the endoplasmic reticulum
- ER-associated degradation
- Overview
- Recognition of misfolded glycoproteins
- The Glyco code of the ER
Links
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Talk Citation
Williams, D.B. (2012, February 2). Role of calnexin and calreticulin in protein homeostasis within the endoplasmic reticulum [Video file]. In
The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved July 3, 2022, from
https://hstalks.com/bs/2221/.
Publication History
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Published on February 2, 2012
Financial Disclosures
- Prof. David B. Williams has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.