TY - ADVS TI - Interleukin-6: back to the future AU - Kishimoto, Tadamitsu PY - 2011 DA - 2011/12/05 UR - https://hstalks.com/bs/2148/ AB - IL-6 is a pleiotropic proinflammatory cytokine, Its overproduction is involved in inflammatory autoimmune diseases including rheumatoid arthritis, Blocking of IL-6 signals by anti-IL6 receptor antibody (Tocilizumab) shows therapeutic effect on various autoimmune diseases, Tocilizumab exerts its effect by inhibiting the induction of a helper T cell subset (TH17), Aryl-hydrocarbon receptor (Ahr) is one of the essential molecule for the IL-6 mediated induction of TH17 cells DB - The Biomedical & Life Sciences Collection SN - 2056-452X ID - 2897 PB - Henry Stewart Talks ER -