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Printable Handouts
Navigable Slide Index
- Introduction
- General pathophysiology of glia
- Reactive astrogliosis - definition
- Anisomorphic and isomorphic astrogliosis
- GFAP upregulation-a hallmark of astrogliosis
- Initiation and regulation of reactive astrogliosis
- Astroglial dichotomy - neuroprotective/neurotoxic
- Alexander's disease (1)
- Alexander's disease (2)
- Astrocytes in ischemia and stroke
- Spatial and temporal progression of stroke (1)
- Spatial and temporal progression of stroke (2)
- Astroglia protect the brain against ischaemia
- Astrocytes may exacerbate brain damage
- Brain oedema
- Brain oedema - consequences
- Hepatic encephalopathy - primary astrocytopathy
- Possible neuroglial roots of neurodegeneration
- Neurodegenerative diseases - specific to humans
- AD - characteristic neurodegeneration
- AD - glial cells form the neuritic plaque
- Absence of astroglial loss in AD model animals
- AD - astroglial atrophy and astrogliosis (1)
- AD - astroglial atrophy and astrogliosis (2)
- Complex changes in microglia during AD
- Astroglial atrophy in neurodegenerative diseases
- Neuroglial hypothesis of neurodegeneration
- Conclusion
Topics Covered
- Reactive astrogliosis
- Anisomorphic and isomorphic astrogliosis
- Up-regulation of GFAP synthesis
- Initiation and regulation of reactive astrogliosis
- Neuroprotection and neurotoxicity
- Alexander's disease
- Astrocytes in ischaemia and stroke
- Brain oedema
- Possible neuroglial roots of neurodegeneration
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Talk Citation
Verkhratsky, A. (2011, June 29). Astroglia in neuropathology [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 7, 2024, from https://doi.org/10.69645/RZAJ3349.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Alexei Verkhratsky has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.