https://hstalks.com/category/762/methods/?biosci New and updated series & talks on Methods from HSTalks' Biomedical & Life Sciences Collection. daily 1 2006-01-01T12:00+00:00 Henry Stewart Talks en © Copyright Henry Stewart Talks Ltd. The Biomedical & Life Sciences Collection © Copyright Henry Stewart Talks Ltd. https://hstalks.com/t/23851/long-term-follow-up-of-gene-therapy-trial-particip/?biosci Long-term follow-up of gene therapy (LTFU) - History of LTFU - Gene therapy registries - Platform trials - Bespoke Gene Therapy Consortium (BGTC) - Mock schedule of assessments - Bayesian hierarchical modelling - EXNEX Long-term follow-up of gene therapy trial participants: practical and statistical considerations Dr. Avery McIntosh Long-term follow-up of gene therapy (LTFU), History of LTFU, Gene therapy registries, Platform trials, Bespoke Gene Therapy Consortium (BGTC), Mock schedule of assessments, Bayesian hierarchical modelling, EXNEX 2026-10-29 2026-10-29 The Biomedical & Life Sciences Collection https://hstalks.com/t/27283/optimizing-collaboration-between-lead-identifiers-/?biosci Computational genomics - Structural variants - Tandem repeats - Long-read sequencing - Genomic variant calling - Epigenetics and methylation - AI and machine learning in genomics - HLA genomics - LPA and cardiovascular disease - Academic-industry collaboration Optimizing collaboration between lead identifiers and genomic analysts in pharma and biotech companies Dr. Fritz Sedlazeck Computational genomics, Structural variants, Tandem repeats, Long-read sequencing, Genomic variant calling, Epigenetics and methylation, AI and machine learning in genomics, HLA genomics, LPA and cardiovascular disease, Academic-industry collaboration 2026-10-29 2026-10-29 The Biomedical & Life Sciences Collection https://hstalks.com/t/27382/in-vitro-vs-in-vivo-vs-in-silico-models/?biosci In vitro, in vivo, in silico models - Applications of model types - Strengths and limitations of each model - Challenges in translating preclinical findings - Integrating multiple models in research - Criteria for selecting research models In vitro vs in vivo vs in silico models In vitro, in vivo, in silico models, Applications of model types, Strengths and limitations of each model, Challenges in translating preclinical findings, Integrating multiple models in research, Criteria for selecting research models 2026-10-29 2026-10-29 The Biomedical & Life Sciences Collection https://hstalks.com/t/27415/protein-purification/?biosci Protein purification basics - Recombinant expression systems - Protein recovery steps - Purification chromatography methods - Analytical yield and purity methods - Scale-up challenges and strategies Protein purification Protein purification basics, Recombinant expression systems, Protein recovery steps, Purification chromatography methods, Analytical yield and purity methods, Scale-up challenges and strategies 2026-10-29 2026-10-29 The Biomedical & Life Sciences Collection https://hstalks.com/t/25666/complex-in-vitro-models-and-the-future-of-drug-saf/?biosci Definition and role of complex In vitro models - Growing importance in drug development - Key messages for the pharmaceutical industry - Challenges to wider industry adoption - Impact on drug safety and efficacy assessment - Future outlook and potential to reduce animal use Complex in vitro models and the future of drug safety and efficacy assessment Dr. Nadine Stokar-Regenscheit Definition and role of complex In vitro models, Growing importance in drug development, Key messages for the pharmaceutical industry, Challenges to wider industry adoption, Impact on drug safety and efficacy assessment, Future outlook and potential to reduce animal use 2026-10-15 2026-10-15 The Biomedical & Life Sciences Collection https://hstalks.com/t/27044/applications-of-cell-culture-in-drug-development/?biosci Cell culture fundamentals - Cell culture requirements - Cell line types in research - Cell culture in drug development - Drug screening using cell culture - Limitations of cell culture models Applications of cell culture in drug development Cell culture fundamentals, Cell culture requirements, Cell line types in research, Cell culture in drug development, Drug screening using cell culture, Limitations of cell culture models 2026-09-30 2026-09-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/27043/rt-pcr-vs-qpcr/?biosci RT-PCR vs qPCR principles - Nucleic acid amplification - CDNA synthesis in RT-PCR - Real-time quantification in qPCR - Endpoint vs real-time analysis - Medical diagnostics applications - Technical challenges and limitations RT-PCR vs qPCR RT-PCR vs qPCR principles, Nucleic acid amplification, CDNA synthesis in RT-PCR, Real-time quantification in qPCR, Endpoint vs real-time analysis, Medical diagnostics applications, Technical challenges and limitations 2026-09-30 2026-09-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/21937/capillary-gel-electrophoresis-2/?biosci High-performance capillary gel electrophoresis (CGE) - Non-denaturing capillary polyacrylamide gel electrophoresis - Micropreparative capillary gel electrophoresis - SDS-PAGE vs. SDS-CGE - Transitionally cross-linked sieving matrices - Coaxial sheath flow reactor CGE-ESI-MS interface - Techniques used for solubilized and immobilized affinity ligands in CGE Capillary gel electrophoresis 2 Prof. Dr. András Guttman High-performance capillary gel electrophoresis (CGE), Non-denaturing capillary polyacrylamide gel electrophoresis, Micropreparative capillary gel electrophoresis, SDS-PAGE vs. SDS-CGE, Transitionally cross-linked sieving matrices, Coaxial sheath flow reactor CGE-ESI-MS interface, Techniques used for solubilized and immobilized affinity ligands in CGE 2026-08-31 2026-08-31 The Biomedical & Life Sciences Collection https://hstalks.com/t/21640/gas-chromatography-an-overview-and-recent-advances/?biosci Overview of gas chromatography (GC) - Packed column GC and capillary column GC - GC×GC - One dimensional GC instrumentation - GC Flame Ionization Detector (GC-FID) - Mass spectrometer: The most important GC detector - Multidimensional chromatography - Heart cutting two dimensional methods - Comprehensive 2D methods Gas chromatography: an overview and recent advances Prof. Dr. Peter Q. Tranchida Overview of gas chromatography (GC), Packed column GC and capillary column GC, GC×GC, One dimensional GC instrumentation, GC Flame Ionization Detector (GC-FID), Mass spectrometer: The most important GC detector, Multidimensional chromatography, Heart cutting two dimensional methods, Comprehensive 2D methods 2026-08-31 2026-08-31 The Biomedical & Life Sciences Collection https://hstalks.com/t/22399/an-introduction-to-genetic-association-analysis/?biosci Basic tests of genetic association - Different genetic models - Genome-Wide Association Study (GWAS) - Polygenic risk score and its applications - Transcriptome- Wide Association Study (TWAS) - Mendelian Randomisation (MR) An introduction to genetic association analysis Dr. Mark Iles Basic tests of genetic association, Different genetic models, Genome-Wide Association Study (GWAS), Polygenic risk score and its applications, Transcriptome- Wide Association Study (TWAS), Mendelian Randomisation (MR) 2026-08-31 2026-08-31 The Biomedical & Life Sciences Collection