https://hstalks.com/category/757/genetics-epigenetics/?biosci New and updated series & talks on Genetics & Epigenetics from HSTalks' Biomedical & Life Sciences Collection. daily 1 2006-01-01T12:00+00:00 Henry Stewart Talks en © Copyright Henry Stewart Talks Ltd. The Biomedical & Life Sciences Collection © Copyright Henry Stewart Talks Ltd. https://hstalks.com/t/12730/bladder-cancer-types-risk-factors-diagnosis-treatm/?biosci Bladder cancer: incidence and epidemiology - Bladder cancer risk factors - Lynch syndrome - Bladder cancer: pathology, staging and diagnosis - Initial therapy for NMIBC (non-muscle-invasive bladder cancer) Bladder cancer: types, risk factors, diagnosis, treatment and prevention: introduction to bladder cancer Prof. Guru P. Sonpavde Bladder cancer: incidence and epidemiology, Bladder cancer risk factors, Lynch syndrome, Bladder cancer: pathology, staging and diagnosis, Initial therapy for NMIBC (non-muscle-invasive bladder cancer) 2026-09-30 2026-09-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/22333/ich-s12-nonclinical-biodistribution-considerations/?biosci Chapters of ICHS12 - Introduction (Objective and scope) - Definition of non-clinical (NC) biodistribution (BD) studies - Timing of BD studies - Design of BD studies - ICHS12: Specific considerations - Applications of BD studies ICH S12: nonclinical biodistribution considerations for gene therapy products Dr. Tineke van den Hoorn Chapters of ICHS12, Introduction (Objective and scope), Definition of non-clinical (NC) biodistribution (BD) studies, Timing of BD studies, Design of BD studies, ICHS12: Specific considerations, Applications of BD studies 2026-09-30 2026-09-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/26062/newborn-screening-how-genome-sequencing-is-changin/?biosci Genome sequencing - Newborn screening - Whole-genome sequencing - Genetic disorders - Immunodeficiency - Health equity - Genomic data interpretation - Population health Newborn screening: how genome sequencing is changing early diagnosis Dr. Wendy Chung Genome sequencing, Newborn screening, Whole-genome sequencing, Genetic disorders, Immunodeficiency, Health equity, Genomic data interpretation, Population health 2026-09-30 2026-09-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/26458/the-case-of-an-asymptomatic-alzheimers-mutation-ca/?biosci Familial Alzheimer’s disease - PSEN1 mutation - Amyloid deposition - Tau pathology - Genetic resilience - Heat shock proteins - Tau-targeted therapies - Precision medicine The case of an asymptomatic Alzheimer’s mutation carrier Dr. Jorge J. Llibre-Guerra Familial Alzheimer’s disease, PSEN1 mutation, Amyloid deposition, Tau pathology, Genetic resilience, Heat shock proteins, Tau-targeted therapies, Precision medicine 2026-09-30 2026-09-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/22399/an-introduction-to-genetic-association-analysis/?biosci Basic tests of genetic association - Different genetic models - Genome-Wide Association Study (GWAS) - Polygenic risk score and its applications - Transcriptome- Wide Association Study (TWAS) - Mendelian Randomisation (MR) An introduction to genetic association analysis Dr. Mark Iles Basic tests of genetic association, Different genetic models, Genome-Wide Association Study (GWAS), Polygenic risk score and its applications, Transcriptome- Wide Association Study (TWAS), Mendelian Randomisation (MR) 2026-08-31 2026-08-31 The Biomedical & Life Sciences Collection https://hstalks.com/t/24745/dna-replication/?biosci DNA structure and function - DNA replication enzymes and steps - Replication origins and fork formation - Leading and lagging strand synthesis - Proofreading and DNA repair mechanisms - Semi-conservative replication model - Cell cycle and chromatin coordination DNA replication DNA structure and function, DNA replication enzymes and steps, Replication origins and fork formation, Leading and lagging strand synthesis, Proofreading and DNA repair mechanisms, Semi-conservative replication model, Cell cycle and chromatin coordination 2026-07-30 2026-07-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/24747/mrna-splicing-and-post-transcriptional-modificatio/?biosci MRNA splicing - RNA modifications - MRNA in gene expression - Spliceosome mechanism - Alternative splicing diversity - 5' capping - 3' polyadenylation - MRNA processing in disease mRNA splicing and post-transcriptional modifications MRNA splicing, RNA modifications, MRNA in gene expression, Spliceosome mechanism, Alternative splicing diversity, 5' capping, 3' polyadenylation, MRNA processing in disease 2026-07-30 2026-07-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/24748/dna-repair-mechanisms/?biosci DNA damage sources and types - DNA repair pathways (BER, NER, MMR) - DNA polymerase and ligase roles - Repair defects in cancer and aging - DNA repair in disease prevention and treatment DNA repair mechanisms DNA damage sources and types, DNA repair pathways (BER, NER, MMR), DNA polymerase and ligase roles, Repair defects in cancer and aging, DNA repair in disease prevention and treatment 2026-07-30 2026-07-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/24750/genome-wide-association-studies-gwas/?biosci Fundamentals of GWAS - GWAS workflow - SNP genotyping and analysis - Statistical thresholds and replication - Polygenic risk scores - GWAS impact in human health - GWAS challenges and ethics Genome-wide association studies (GWAS) Fundamentals of GWAS, GWAS workflow, SNP genotyping and analysis, Statistical thresholds and replication, Polygenic risk scores, GWAS impact in human health, GWAS challenges and ethics 2026-07-30 2026-07-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/24746/histone-modifications-and-epigenetics/?biosci Nucleosome structure and function - Main histone modifications - Histone modifications effect on gene expression - Histone code and cellular memory - Histone modifications in development - Histone modifications in disease and cancer - Targeting histone-modifying enzymes therapeutically Histone modifications and epigenetics Nucleosome structure and function, Main histone modifications, Histone modifications effect on gene expression, Histone code and cellular memory, Histone modifications in development, Histone modifications in disease and cancer, Targeting histone-modifying enzymes therapeutically 2026-07-30 2026-07-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/24757/rna-vs-dna-viruses/?biosci RNA vs DNA viruses - Genetic material differences - Replication strategies - Mutation rates and adaptability - Pathogenesis impacts - Immune system interactions - Virus examples - Vaccine development - Antiviral treatment options RNA vs DNA viruses RNA vs DNA viruses, Genetic material differences, Replication strategies, Mutation rates and adaptability, Pathogenesis impacts, Immune system interactions, Virus examples, Vaccine development, Antiviral treatment options 2026-07-30 2026-07-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/20617/cell-replacement-therapy-for-neurodegenerative-dis/?biosci Huntington’s disease (HD) - Genetics, symptoms and pathology of HD - Transplants in HD - Stem cell derived medium spiny neurons - hPSC-derived medium spiny neurons Cell replacement therapy for neurodegenerative diseases 2 Dr. Mariah J. Lelos Huntington’s disease (HD), Genetics, symptoms and pathology of HD, Transplants in HD, Stem cell derived medium spiny neurons, hPSC-derived medium spiny neurons 2026-07-30 2026-07-30 The Biomedical & Life Sciences Collection