https://hstalks.com/category/757/genetics-epigenetics/?biosci New and updated series & talks on Genetics & Epigenetics from HSTalks' Biomedical & Life Sciences Collection. daily 1 2006-01-01T12:00+00:00 Henry Stewart Talks en © Copyright Henry Stewart Talks Ltd. The Biomedical & Life Sciences Collection © Copyright Henry Stewart Talks Ltd. https://hstalks.com/playlist/2205/developing-gene-therapies/?biosci Core principles of gene therapy (GTx) product development - Unmet medical needs addressed by GTx - Emerging business models, industry standards and best practices for GTx - Statistical design and analysis aspects of clinical trials of GTx - Case studies of successful development of GTx - Emerging global regulatory pathways for GTx - Benefits of GTx in the coming years from a multi-stakeholder perspective Developing Gene Therapies Dr. Avery McIntosh Dr. Alex Sverdlov Core principles of gene therapy (GTx) product development, Unmet medical needs addressed by GTx, Emerging business models, industry standards and best practices for GTx, Statistical design and analysis aspects of clinical trials of GTx, Case studies of successful development of GTx, Emerging global regulatory pathways for GTx, Benefits of GTx in the coming years from a multi-stakeholder perspective 2026-10-29 2026-10-29 The Biomedical & Life Sciences Collection https://hstalks.com/t/27283/optimizing-collaboration-between-lead-identifiers-/?biosci Computational genomics - Structural variants - Tandem repeats - Long-read sequencing - Genomic variant calling - Epigenetics and methylation - AI and machine learning in genomics - HLA genomics - LPA and cardiovascular disease - Academic-industry collaboration Optimizing collaboration between lead identifiers and genomic analysts in pharma and biotech companies Dr. Fritz Sedlazeck Computational genomics, Structural variants, Tandem repeats, Long-read sequencing, Genomic variant calling, Epigenetics and methylation, AI and machine learning in genomics, HLA genomics, LPA and cardiovascular disease, Academic-industry collaboration 2026-10-29 2026-10-29 The Biomedical & Life Sciences Collection https://hstalks.com/t/23026/gene-therapies-economics-access-barriers-commercia/?biosci Gene therapy - Rare diseases - Economic challenges of gene therapies - Patient access - Real world evidences - Health technology assessment - Patient advocacy groups - Clinical development plan - Market development plant Gene therapies: economics, access barriers & commercial models Dr. Kasem S. Akhras Gene therapy, Rare diseases, Economic challenges of gene therapies, Patient access, Real world evidences, Health technology assessment, Patient advocacy groups, Clinical development plan, Market development plant 2026-10-29 2026-10-29 The Biomedical & Life Sciences Collection https://hstalks.com/t/24084/the-environment-scleroderma/?biosci Systemic sclerosis (scleroderma) - Pathogenesis of systemic sclerosis (SSc) - Gene-susceptibility and gene-environment interaction in SSc - Environmental risk factors - Epigenetic impact of toxins - Infectious triggers - Microbiome alteration in SSc - Medications associated with scleroderma-like skin changes or scleroderma The environment & scleroderma Dr. Zsuzsanna McMahan Systemic sclerosis (scleroderma), Pathogenesis of systemic sclerosis (SSc), Gene-susceptibility and gene-environment interaction in SSc, Environmental risk factors, Epigenetic impact of toxins, Infectious triggers, Microbiome alteration in SSc, Medications associated with scleroderma-like skin changes or scleroderma 2026-10-29 2026-10-29 The Biomedical & Life Sciences Collection https://hstalks.com/t/23455/new-standards-in-weight-management/?biosci Trends in obesity - Strategies for obesity prevention - Interventions for treatment of obesity - Approved drugs for obesity treatment - Obesity management - Clinical trials New standards in weight management Prof. John Wilding Trends in obesity, Strategies for obesity prevention, Interventions for treatment of obesity, Approved drugs for obesity treatment, Obesity management, Clinical trials 2026-10-29 2026-10-29 The Biomedical & Life Sciences Collection https://hstalks.com/t/22762/regulatory-considerations-in-the-development-of-ge/?biosci Introduction to regulatory considerations in the development of gene therapy products - Regulatory definitions of gene therapy - Designations and expedited pathways - Unique regulatory considerations for gene therapy - Emerging regulatory trends Regulatory considerations in the development of gene therapy products Dr. Seoan Huh Introduction to regulatory considerations in the development of gene therapy products, Regulatory definitions of gene therapy, Designations and expedited pathways, Unique regulatory considerations for gene therapy, Emerging regulatory trends 2026-10-29 2026-10-29 The Biomedical & Life Sciences Collection https://hstalks.com/t/26458/the-case-of-an-asymptomatic-alzheimers-mutation-ca/?biosci Familial Alzheimer’s disease - PSEN1 mutation - Amyloid deposition - Tau pathology - Genetic resilience - Heat shock proteins - Tau-targeted therapies - Precision medicine The case of an asymptomatic Alzheimer’s mutation carrier Dr. Jorge J. Llibre-Guerra Familial Alzheimer’s disease, PSEN1 mutation, Amyloid deposition, Tau pathology, Genetic resilience, Heat shock proteins, Tau-targeted therapies, Precision medicine 2026-09-30 2026-09-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/26062/newborn-screening-how-genome-sequencing-is-changin/?biosci Genome sequencing - Newborn screening - Whole-genome sequencing - Genetic disorders - Immunodeficiency - Health equity - Genomic data interpretation - Population health Newborn screening: how genome sequencing is changing early diagnosis Dr. Wendy Chung Genome sequencing, Newborn screening, Whole-genome sequencing, Genetic disorders, Immunodeficiency, Health equity, Genomic data interpretation, Population health 2026-09-30 2026-09-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/12730/bladder-cancer-types-risk-factors-diagnosis-treatm/?biosci Bladder cancer: incidence and epidemiology - Bladder cancer risk factors - Lynch syndrome - Bladder cancer: pathology, staging and diagnosis - Initial therapy for NMIBC (non-muscle-invasive bladder cancer) Bladder cancer: types, risk factors, diagnosis, treatment and prevention: introduction to bladder cancer Prof. Guru P. Sonpavde Bladder cancer: incidence and epidemiology, Bladder cancer risk factors, Lynch syndrome, Bladder cancer: pathology, staging and diagnosis, Initial therapy for NMIBC (non-muscle-invasive bladder cancer) 2026-09-30 2026-09-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/22333/ich-s12-nonclinical-biodistribution-considerations/?biosci Chapters of ICHS12 - Introduction (Objective and scope) - Definition of non-clinical (NC) biodistribution (BD) studies - Timing of BD studies - Design of BD studies - ICHS12: Specific considerations - Applications of BD studies ICH S12: nonclinical biodistribution considerations for gene therapy products Dr. Tineke van den Hoorn Chapters of ICHS12, Introduction (Objective and scope), Definition of non-clinical (NC) biodistribution (BD) studies, Timing of BD studies, Design of BD studies, ICHS12: Specific considerations, Applications of BD studies 2026-09-30 2026-09-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/22399/an-introduction-to-genetic-association-analysis/?biosci Basic tests of genetic association - Different genetic models - Genome-Wide Association Study (GWAS) - Polygenic risk score and its applications - Transcriptome- Wide Association Study (TWAS) - Mendelian Randomisation (MR) An introduction to genetic association analysis Dr. Mark Iles Basic tests of genetic association, Different genetic models, Genome-Wide Association Study (GWAS), Polygenic risk score and its applications, Transcriptome- Wide Association Study (TWAS), Mendelian Randomisation (MR) 2026-08-31 2026-08-31 The Biomedical & Life Sciences Collection