https://hstalks.com/category/755/biochemistry/?biosci New and updated series & talks on Biochemistry from HSTalks' Biomedical & Life Sciences Collection. daily 1 2006-01-01T12:00+00:00 Henry Stewart Talks en © Copyright Henry Stewart Talks Ltd. The Biomedical & Life Sciences Collection © Copyright Henry Stewart Talks Ltd. https://hstalks.com/t/16855/gene-manipulation-applications-in-autoimmune-disea/?biosci Autoimmunity - Type 1 diabetes (T1D) - T cell-mediated immune tolerance - Regulatory T cells (Tregs) - FOXP3 gene - Central and peripheral immune tolerance Gene manipulation applications in autoimmune diseases 1 Dr. Leonardo M. R. Ferreira Autoimmunity, Type 1 diabetes (T1D), T cell-mediated immune tolerance, Regulatory T cells (Tregs), FOXP3 gene, Central and peripheral immune tolerance 2026-04-30 2026-04-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/17482/gene-manipulation-applications-in-autoimmune-disea/?biosci Chimeric antigen receptor (CAR) - Islet transplantation for T1D treatment - Treating T1D using islet transplant and CAR Tregs - Genetic modifications of human Treg - Reprogramming human Treg specificity Gene manipulation applications in autoimmune diseases 2 Dr. Leonardo M. R. Ferreira Chimeric antigen receptor (CAR), Islet transplantation for T1D treatment, Treating T1D using islet transplant and CAR Tregs, Genetic modifications of human Treg, Reprogramming human Treg specificity 2026-04-30 2026-04-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/21053/enzymes-in-drug-metabolism/?biosci Role of enzymes in drug metabolism - Phases of drug metabolism - Cytochrome P450 enzyme functions - Conjugating enzymes in Phase Two - Influences on enzyme activity - Enzyme induction and inhibition - Pharmacogenomics in personalized medicine Enzymes in drug metabolism Role of enzymes in drug metabolism, Phases of drug metabolism, Cytochrome P450 enzyme functions, Conjugating enzymes in Phase Two, Influences on enzyme activity, Enzyme induction and inhibition, Pharmacogenomics in personalized medicine 2026-04-30 2026-04-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/1892/smad-phosphorylation-and-the-tgf-beta-pathway/?biosci The TGFb family as a paradigm of multifunctional cytokines - TGFb controlling embryo development and tissue homeostasis - TGFb receptor serine/threonine kinases - SMADs as central TGFb signal transducers and transcriptional mediators - Logic and organization of TGFb signaling processes - TGFb pathway regulation and integration in the cell - TGFb pathway disruption in heritable disorders and cancer SMAD phosphorylation and the TGF-beta pathway Prof. Joan Massagué The TGFb family as a paradigm of multifunctional cytokines, TGFb controlling embryo development and tissue homeostasis, TGFb receptor serine/threonine kinases, SMADs as central TGFb signal transducers and transcriptional mediators, Logic and organization of TGFb signaling processes, TGFb pathway regulation and integration in the cell, TGFb pathway disruption in heritable disorders and cancer 2026-04-30 2026-04-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/17483/gene-manipulation-applications-in-autoimmune-disea/?biosci Gene manipulation of cell types targeted by immune attack - Universal stem cells - Human hypoimmune stem cell-derived pancreatic islets - Functional stem cell-derived beta cells (sBC) for therapy - CAR Tregs for therapy Gene manipulation applications in autoimmune diseases 3 Dr. Leonardo M. R. Ferreira Gene manipulation of cell types targeted by immune attack, Universal stem cells, Human hypoimmune stem cell-derived pancreatic islets, Functional stem cell-derived beta cells (sBC) for therapy, CAR Tregs for therapy 2026-04-30 2026-04-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/17416/intellectual-property-and-patents/?biosci Drug patent - Intellectual property rules and regulations - Drug development costs - IP protection period - Drug development economics - Patent suitability - Patent transfer Intellectual property and patents Dr. Wayne Carter Drug patent, Intellectual property rules and regulations, Drug development costs, IP protection period, Drug development economics, Patent suitability, Patent transfer 2026-04-30 2026-04-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/19867/integration-of-metabolism/?biosci Catabolic and anabolic pathway integration - Key metabolic processes - Gluconeogenesis regulation - Hormonal coordination in metabolism - Metabolite and allosteric regulation - ATP production adaptation - Metabolic integration in health and disease Integration of metabolism Catabolic and anabolic pathway integration, Key metabolic processes, Gluconeogenesis regulation, Hormonal coordination in metabolism, Metabolite and allosteric regulation, ATP production adaptation, Metabolic integration in health and disease 2026-03-31 2026-03-31 The Biomedical & Life Sciences Collection https://hstalks.com/t/17582/streptococcus-pyogenes-disease-and-molecular-patho/?biosci Streptococcal species - Streptococcus agalactiae -S. pneumoniae - S. pyogenes - S. pyogenes infections - Rheumatic fever - Acute post-streptococcal glomerulonephritis (APSGN) Streptococcus pyogenes: disease and molecular pathogenesis 1 Prof. P. Patrick Cleary Streptococcal species, Streptococcus agalactiae -S. pneumoniae, S. pyogenes, S. pyogenes infections, Rheumatic fever, Acute post-streptococcal glomerulonephritis (APSGN) 2026-03-31 2026-03-31 The Biomedical & Life Sciences Collection https://hstalks.com/t/18441/de-novo-designed-proteins-a-breakthrough-in-snakeb/?biosci De novo protein design - Snakebite envenoming & antivenom development - Computational protein engineering - Deep learning tools - In vitro and in vivo validation - Global health and democratization of drug discovery De novo designed proteins: a breakthrough in snakebite treatment Dr. Susana Vazquez Torres De novo protein design, Snakebite envenoming & antivenom development, Computational protein engineering, Deep learning tools, In vitro and in vivo validation, Global health and democratization of drug discovery 2026-03-31 2026-03-31 The Biomedical & Life Sciences Collection https://hstalks.com/t/9166/the-pre-analytical-phase-of-laboratory-medicine/?biosci Pre-analytical phase - Total testing process - Laboratory and diagnostic errors - Blood specimen quality - Financial impact of pre-analytical errors - Sources of pre-analytical variability - Phlebotomy - Hemolysis The pre-analytical phase of laboratory medicine Prof. Giuseppe Lippi Pre-analytical phase, Total testing process, Laboratory and diagnostic errors, Blood specimen quality, Financial impact of pre-analytical errors, Sources of pre-analytical variability, Phlebotomy, Hemolysis 2026-03-31 2026-03-31 The Biomedical & Life Sciences Collection https://hstalks.com/t/17581/streptococcus-pyogenes-disease-and-molecular-patho/?biosci S. pyogenes - Resistance to phagocytosis - C5a peptidase - Human C5a - M protein - Superantigens - Adhesins and invasins Streptococcus pyogenes: disease and molecular pathogenesis 2 Prof. P. Patrick Cleary S. pyogenes, Resistance to phagocytosis, C5a peptidase, Human C5a, M protein, Superantigens, Adhesins and invasins 2026-03-31 2026-03-31 The Biomedical & Life Sciences Collection https://hstalks.com/playlist/1380/clinical-biochemistry/?biosci Foundations of clinical laboratory medicine - Pre-analytical, analytical & biological variability - Core laboratory techniques & methodologies - Hematology & transfusion medicine - Clinical chemistry & organ function testing - Disease-specific biomarkers - Emerging & advanced fields - Quality, standardization & global perspectives Clinical Biochemistry Dr. Anna Carobene Foundations of clinical laboratory medicine, Pre-analytical, analytical & biological variability, Core laboratory techniques & methodologies, Hematology & transfusion medicine, Clinical chemistry & organ function testing, Disease-specific biomarkers, Emerging & advanced fields, Quality, standardization & global perspectives 2026-02-26 2026-02-26 The Biomedical & Life Sciences Collection https://hstalks.com/t/18567/western-blotting-for-protein-detection/?biosci Western blotting principles - Protein extraction methods - SDS-PAGE protein separation - Membrane transfer and blocking - Antibody detection methods - Detection and quantification - Applications and limitations - Specificity and reliability - Advances in normalization Western blotting for protein detection Western blotting principles, Protein extraction methods, SDS-PAGE protein separation, Membrane transfer and blocking, Antibody detection methods, Detection and quantification, Applications and limitations, Specificity and reliability, Advances in normalization 2026-02-26 2026-02-26 The Biomedical & Life Sciences Collection https://hstalks.com/t/16525/clinical-biochemistry-introduction/?biosci History of medicine - Modern medicine - Laboratory innovation - Measurement in laboratories - Precision and accuracy in laboratory measurements - Standardization and harmonization in laboratory measurements - Classification of laboratory measurements: Direct measurements - Biological variation - Total testing process - Laboratory medicine Clinical biochemistry: introduction Dr. Anna Carobene History of medicine, Modern medicine, Laboratory innovation, Measurement in laboratories, Precision and accuracy in laboratory measurements, Standardization and harmonization in laboratory measurements, Classification of laboratory measurements: Direct measurements, Biological variation, Total testing process, Laboratory medicine 2026-02-26 2026-02-26 The Biomedical & Life Sciences Collection https://hstalks.com/t/18558/acid-base-balance-and-buffer-systems/?biosci Acid-base balance and physiological pH - Buffer systems and bicarbonate - Respiratory acid-base regulation - Renal pH regulation mechanisms - Clinical acid-base disturbances - Homeostasis and physiological challenges Acid-base balance and buffer systems Acid-base balance and physiological pH, Buffer systems and bicarbonate, Respiratory acid-base regulation, Renal pH regulation mechanisms, Clinical acid-base disturbances, Homeostasis and physiological challenges 2026-02-26 2026-02-26 The Biomedical & Life Sciences Collection https://hstalks.com/t/16228/introduction-to-mass-spectrometry-2/?biosci Mass analyzer - Ion detectors - Tandem Mass Spectrometry (MS/MS) - Key MS applications: proteomics and imaging - Native MS - Ion Mobility (IM)-MS - Chemical modifications strategies Introduction to mass spectrometry 2 Prof. Brandon T. Ruotolo Mass analyzer, Ion detectors, Tandem Mass Spectrometry (MS/MS), Key MS applications: proteomics and imaging, Native MS, Ion Mobility (IM)-MS, Chemical modifications strategies 2026-02-26 2026-02-26 The Biomedical & Life Sciences Collection https://hstalks.com/t/9562/introduction-to-mass-spectrometry-1/?biosci Mass Spectrometry (MS) - Mass spectrum - Mass-to-charge (m/z) ratio of ions - Ion sources in mass spectroscopy - Mass resolving power and mass resolution - Electron Impact Ionization (EI) - Chemical Ionization (CI) - Electrospray Ionization (ESI) - Matrix-assisted Laser Desorption Ionization (MALDI) Introduction to mass spectrometry 1 Prof. Brandon T. Ruotolo Mass Spectrometry (MS), Mass spectrum, Mass-to-charge (m/z) ratio of ions, Ion sources in mass spectroscopy, Mass resolving power and mass resolution, Electron Impact Ionization (EI), Chemical Ionization (CI), Electrospray Ionization (ESI), Matrix-assisted Laser Desorption Ionization (MALDI) 2026-02-26 2026-02-26 The Biomedical & Life Sciences Collection https://hstalks.com/t/14776/oncological-biomarkers/?biosci Tumor markers in the current and future clinical practice - Methods for tumor marker detection - International Standards (IS) & Reference Preparations (IRP) - Combining tumor markers for improving diagnostic performance - Clinical uses of tumor markers - Genetic markers Oncological biomarkers Prof. Dr. Tomris Ozben Tumor markers in the current and future clinical practice, Methods for tumor marker detection, International Standards (IS) & Reference Preparations (IRP), Combining tumor markers for improving diagnostic performance, Clinical uses of tumor markers, Genetic markers 2026-02-26 2026-02-26 The Biomedical & Life Sciences Collection