https://hstalks.com/category/754/pharmaceutical-sciences/?biosci New and updated series & talks on Pharmaceutical Sciences from HSTalks' Biomedical & Life Sciences Collection. daily 1 2006-01-01T12:00+00:00 Henry Stewart Talks en © Copyright Henry Stewart Talks Ltd. The Biomedical & Life Sciences Collection © Copyright Henry Stewart Talks Ltd. https://hstalks.com/playlist/1941/regulatory-ich-guidelines-with-nonclinical-impact/?biosci M4 Common Technical Dossier - M3 Nonclinical Requirements for Clinical Trials, First-in-Human - S1A/C Carcinogenicity Studies: When are they Needed/ Dose Selection - S1B Testing Carcinogenic Potential of Human Pharmaceuticals, Transgenic Models - S6 Preclinical Requirements for Biotechnology-derived Products - S7 Safety Pharmacology - S8 Immunotoxicity - S11 Juvenile Toxicity Testing - 1B(R1) Testing Carcinogenic Potential of Human Pharmaceuticals Approach - S2 Genotoxicity - S3 Pharmacokinetics - S4 Chronic Toxicity- S5 Reproductive Toxicity Testing - S9 Testing of anticancer compounds - S10 Photosafety - S12 Nonclinical Safety Testing of Gene Therapy Regulatory ICH Guidelines with Nonclinical Impact Dr. Jan Willem van der Laan M4 Common Technical Dossier, M3 Nonclinical Requirements for Clinical Trials, First-in-Human, S1A/C Carcinogenicity Studies: When are they Needed/ Dose Selection, S1B Testing Carcinogenic Potential of Human Pharmaceuticals, Transgenic Models, S6 Preclinical Requirements for Biotechnology-derived Products, S7 Safety Pharmacology, S8 Immunotoxicity, S11 Juvenile Toxicity Testing, 1B(R1) Testing Carcinogenic Potential of Human Pharmaceuticals Approach, S2 Genotoxicity, S3 Pharmacokinetics, S4 Chronic Toxicity- S5 Reproductive Toxicity Testing, S9 Testing of anticancer compounds, S10 Photosafety, S12 Nonclinical Safety Testing of Gene Therapy 2026-03-31 2026-03-31 The Biomedical & Life Sciences Collection https://hstalks.com/t/17614/m4-common-technical-dossier/?biosci CTD triangle - Nonclinical overview - Nonclinical written summaries - Assessment reports - Appendices M4 common technical dossier Dr. Jan Willem van der Laan CTD triangle, Nonclinical overview, Nonclinical written summaries, Assessment reports, Appendices 2026-03-31 2026-03-31 The Biomedical & Life Sciences Collection https://hstalks.com/t/17251/advanced-therapies-in-an-evolving-regulatory-and-a/?biosci Pharma legislation - ATMPs situation in EU - Role of academia in development of advanced therapies - Strategies for translating therapies from Idea to Patient Care - Manufacturing Do’s and Don’ts Advanced therapies in an evolving regulatory and access environment Dr. Ana Hidalgo-Simon Pharma legislation, ATMPs situation in EU, Role of academia in development of advanced therapies, Strategies for translating therapies from Idea to Patient Care, Manufacturing Do’s and Don’ts 2026-03-31 2026-03-31 The Biomedical & Life Sciences Collection https://hstalks.com/t/18241/nonclinical-safety-testing-of-human-pharmaceutical/?biosci ICH participants and ICH safety topics - Benefit-risk assessment - ICH M3: Mother of all guidelines - Guidance history on first-in-human (FIH) starting dose - ICH S7A: Safety pharmacology studies - S7B: Non-clinical testing strategy - Genotoxicity testing - ICH S4: Single and repeated dose toxicity studies Nonclinical safety testing of human pharmaceuticals in relation to clinical development Dr. Jan Willem van der Laan ICH participants and ICH safety topics, Benefit-risk assessment, ICH M3: Mother of all guidelines, Guidance history on first-in-human (FIH) starting dose, ICH S7A: Safety pharmacology studies, S7B: Non-clinical testing strategy, Genotoxicity testing, ICH S4: Single and repeated dose toxicity studies 2026-03-31 2026-03-31 The Biomedical & Life Sciences Collection https://hstalks.com/t/17086/ich-s3a-and-s3b-toxicokinetics-and-pharmacokinetic/?biosci ICH establishment & guidelines - Pharmacokinetics - Toxicokinetics - Microsampling ICH S3A and S3B toxicokinetics and pharmacokinetics Dr. David R. Jones ICH establishment & guidelines, Pharmacokinetics, Toxicokinetics, Microsampling 2026-03-31 2026-03-31 The Biomedical & Life Sciences Collection https://hstalks.com/t/16690/muscarinic-acetylcholine-receptor-modulation-in-ne/?biosci Muscarinic acetylcholine receptors - Neurological drug discovery - Schizophrenia and Alzheimer’s disease - Structure-based drug design - Allosteric GPCR modulation Muscarinic acetylcholine receptor modulation in neurological diseases Prof. Andrew B. Tobin Muscarinic acetylcholine receptors, Neurological drug discovery, Schizophrenia and Alzheimer’s disease, Structure-based drug design, Allosteric GPCR modulation 2026-03-31 2026-03-31 The Biomedical & Life Sciences Collection https://hstalks.com/t/16888/use-of-cholera-vaccine-in-bangladesh-success-and-s/?biosci Cholera vaccination stats of Bangladesh - Vaccine research and development for cholera in Bangladesh - Bangladesh cholera vaccination for Rohingya refugees - Cholera sources - Cholera prevention - Cholera strains Use of cholera vaccine in Bangladesh: success and struggles Dr. Firdausi Qadri Cholera vaccination stats of Bangladesh, Vaccine research and development for cholera in Bangladesh, Bangladesh cholera vaccination for Rohingya refugees, Cholera sources, Cholera prevention, Cholera strains 2026-03-31 2026-03-31 The Biomedical & Life Sciences Collection https://hstalks.com/t/19860/receptor-types-and-drug-targets/?biosci Receptor types and classes - Drug-receptor interaction mechanisms - Major drug targets - Target selectivity and side effects - Roles of agonists, antagonists, modulators - Genetic variability in personalized medicine Receptor types and drug targets Receptor types and classes, Drug-receptor interaction mechanisms, Major drug targets, Target selectivity and side effects, Roles of agonists, antagonists, modulators, Genetic variability in personalized medicine 2026-03-31 2026-03-31 The Biomedical & Life Sciences Collection https://hstalks.com/t/18549/antihypertensives/?biosci Hypertension management for CV risk - Antihypertensive drug classes and mechanisms - Antihypertensive side effects and prescribing - Therapy tailored by comorbidity and ethnicity - Monitoring and patient involvement - Antihypertensive combination therapy - Special considerations in diabetes and CKD Antihypertensives Hypertension management for CV risk, Antihypertensive drug classes and mechanisms, Antihypertensive side effects and prescribing, Therapy tailored by comorbidity and ethnicity, Monitoring and patient involvement, Antihypertensive combination therapy, Special considerations in diabetes and CKD 2026-02-26 2026-02-26 The Biomedical & Life Sciences Collection https://hstalks.com/t/14974/virtual-screening-personal-reflections-and-future-/?biosci Virtual Screening - Structure-based vs. ligand-based - Virtual screening case studies - Cryo-electron microscopy - AI: docking and scoring Virtual screening: personal reflections and future directions Dr. David E. Clark Virtual Screening, Structure-based vs. ligand-based, Virtual screening case studies, Cryo-electron microscopy, AI: docking and scoring 2026-02-26 2026-02-26 The Biomedical & Life Sciences Collection https://hstalks.com/t/15898/ai-based-regulatory-compliance-in-drug-development/?biosci Artificial intelligence (AI) - Regulatory frameworks - Data heterogeneity - Ethical and transparency concerns - Data-driven decision making - Algorithmic transparency and interpretability - Regulatory innovation and technological integration AI-based regulatory compliance in drug development Dr. Antonio Pesqueira Artificial intelligence (AI), Regulatory frameworks, Data heterogeneity, Ethical and transparency concerns, Data-driven decision making, Algorithmic transparency and interpretability, Regulatory innovation and technological integration 2026-02-26 2026-02-26 The Biomedical & Life Sciences Collection https://hstalks.com/t/15040/cochrane-databases-history-utility-1/?biosci Cochrane history, organization and structure - Cochrane Database of Systematic Reviews (CDSR) - Types of Cochrane reviews - Cochrane Central Register of Controlled Trials (CENTRAL) - The creation and maintenance of CENTRAL Cochrane databases: history & utility 1 Dr. Riaz Qureshi Cochrane history, organization and structure, Cochrane Database of Systematic Reviews (CDSR), Types of Cochrane reviews, Cochrane Central Register of Controlled Trials (CENTRAL), The creation and maintenance of CENTRAL 2026-02-26 2026-02-26 The Biomedical & Life Sciences Collection https://hstalks.com/t/15041/cochrane-databases-history-utility-2/?biosci Searching CDSR and CENTRAL - Different search options in Cochrane database - Searching the CDSR: Pro-tips - Online training and interactive learning from Cochrane - Cochrane crowd - Cochrane handbook Cochrane databases: history & utility 2 Dr. Riaz Qureshi Searching CDSR and CENTRAL, Different search options in Cochrane database, Searching the CDSR: Pro-tips, Online training and interactive learning from Cochrane, Cochrane crowd, Cochrane handbook 2026-02-26 2026-02-26 The Biomedical & Life Sciences Collection https://hstalks.com/t/16624/what-i-do-director-of-biostatistics/?biosci Clinical trial design - Biostatistics - Statistical analysis - Real-world evidence - Patient-reported outcomes - Gene therapy - Regulatory submissions - Data modelling What I do: director of biostatistics Dr. Avery McIntosh Clinical trial design, Biostatistics, Statistical analysis, Real-world evidence, Patient-reported outcomes, Gene therapy, Regulatory submissions, Data modelling 2026-02-26 2026-02-26 The Biomedical & Life Sciences Collection https://hstalks.com/t/18548/dose-response-curves-and-therapeutic-index/?biosci Dose-response curves - Potency and efficacy - EC50 and LD50 - Therapeutic index - Patient factors in drug response Dose-response curves and therapeutic index Dose-response curves, Potency and efficacy, EC50 and LD50, Therapeutic index, Patient factors in drug response 2026-02-26 2026-02-26 The Biomedical & Life Sciences Collection https://hstalks.com/t/14809/next-generation-microneedle-technologies-for-drug-/?biosci Next generation microneedle technologies for drug & vaccine delivery Prof. Ryan F. Donnelly 2026-02-24 2026-02-24 The Biomedical & Life Sciences Collection