https://hstalks.com/category/754/pharmaceutical-sciences/?biosci New and updated series & talks on Pharmaceutical Sciences from HSTalks' Biomedical & Life Sciences Collection. daily 1 2006-01-01T12:00+00:00 Henry Stewart Talks en © Copyright Henry Stewart Talks Ltd. The Biomedical & Life Sciences Collection © Copyright Henry Stewart Talks Ltd. https://hstalks.com/t/21838/current-emerging-therapies-for-the-management-of-p/?biosci Endometrial cancer - Classification of endometrial cancer - Single agent immunotherapy in biomarker selected endometrial cancers - First-line treatment of advanced or recurrent endometrial cancer - Adding PARP inhibition to first line - Adjuvant therapy - Antibody drug conjugates in endometrial cancer - Cell cycle checkpoint inhibitors in endometrial cancers - Hormonal therapy - Biomarker based therapy Current & emerging therapies for the management of patients with endometrial cancer Prof. Brian Slomovitz Endometrial cancer, Classification of endometrial cancer, Single agent immunotherapy in biomarker selected endometrial cancers, First-line treatment of advanced or recurrent endometrial cancer, Adding PARP inhibition to first line, Adjuvant therapy, Antibody drug conjugates in endometrial cancer, Cell cycle checkpoint inhibitors in endometrial cancers, Hormonal therapy, Biomarker based therapy 2026-07-30 2026-07-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/20947/ich-s2-genotoxicity/?biosci ICH S2A & S2B guidelines - Standard battery for genotoxicity testing in S2B - Major revised points of the S2(R1) guideline - In vitro & in vivo genotoxicity tests - Revisions to guidelines ICH S2 genotoxicity Dr. Masamitsu Honma ICH S2A & S2B guidelines, Standard battery for genotoxicity testing in S2B, Major revised points of the S2(R1) guideline, In vitro & in vivo genotoxicity tests, Revisions to guidelines 2026-07-30 2026-07-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/18440/drug-refinement/?biosci Hit and lead - High throughput screening - Lead optimisation - Cycle of drug testing - Drug optimisation and refinement Drug refinement Dr. Wayne Carter Hit and lead, High throughput screening, Lead optimisation, Cycle of drug testing, Drug optimisation and refinement 2026-07-30 2026-07-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/23389/unlocking-a-cryptic-pocket-a-new-approach-to-safer/?biosci CB1 receptor agonists - Cryptic pocket drug design - Molecular dynamics simulations - Peripheral pain therapeutics - Biased GPCR signalling - Tolerance reduction in cannabinoid therapies - Allosteric/sodium binding sites - Translation of analgesic drug candidates (VIP36) to the clinic Unlocking a cryptic pocket: a new approach to safer pain relief Prof. Susruta Majumdar Dr. Vipin Ashok Rangari CB1 receptor agonists, Cryptic pocket drug design, Molecular dynamics simulations, Peripheral pain therapeutics, Biased GPCR signalling, Tolerance reduction in cannabinoid therapies, Allosteric/sodium binding sites, Translation of analgesic drug candidates (VIP36) to the clinic 2026-07-30 2026-07-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/21783/emergency-drug-administration-paramedic-context/?biosci Emergency drug admin principles - Rapid accurate drug delivery - Drug delivery routes and selection - Common emergency medications overview - Patient assessment and monitoring - Documentation and communication in emergency care Emergency drug administration (paramedic context) Emergency drug admin principles, Rapid accurate drug delivery, Drug delivery routes and selection, Common emergency medications overview, Patient assessment and monitoring, Documentation and communication in emergency care 2026-06-30 2026-06-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/20221/raav-gene-therapy-manufacturing-analysis-comparabi/?biosci Manufacturing process overview - Development and challenges in manufacturing process - Analytical considerations: critical quality attributes and challenges - Comparability assessment - Evaluation of analytical comparability results - Key regulatory guidance on comparability - Summary of statistical methods - Equivalence test rAAV gene therapy: manufacturing, analysis & comparability Dr. Courtney Sloan Dr. Aili Cheng Manufacturing process overview, Development and challenges in manufacturing process, Analytical considerations: critical quality attributes and challenges, Comparability assessment, Evaluation of analytical comparability results, Key regulatory guidance on comparability, Summary of statistical methods, Equivalence test 2026-06-30 2026-06-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/17779/drug-pharmacokinetics/?biosci Drug metabolism - ADME - Designing drugs - Route of administration - Drug delivery - Characteristics of a successful drug Drug pharmacokinetics Dr. Wayne Carter Drug metabolism, ADME, Designing drugs, Route of administration, Drug delivery, Characteristics of a successful drug 2026-06-30 2026-06-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/19957/interpreting-non-clinical-toxicity-studies-in-psyc/?biosci Psychiatric drug development - Challenges in early drug development - Challenges associated with lifelong treatment - Non-clinical toxicity studies - Toxicity studies for psychiatric therapeutics - Relevance to human safety Interpreting non-clinical toxicity studies in psychiatric drug development: human relevance and safety Dr. Yael Mandelblat-Cerf Psychiatric drug development, Challenges in early drug development, Challenges associated with lifelong treatment, Non-clinical toxicity studies, Toxicity studies for psychiatric therapeutics, Relevance to human safety 2026-06-30 2026-06-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/18439/chemical-synthesis/?biosci Synthesis of chemical entities - Rational drug design - Compound libraries - Phytochemicals as drugs - Scale up Chemical synthesis Dr. Wayne Carter Synthesis of chemical entities, Rational drug design, Compound libraries, Phytochemicals as drugs, Scale up 2026-06-30 2026-06-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/22564/sterile-technique-in-the-lab/?biosci Sterile technique principles - Hand hygiene practices - PPE usage - Sterilization methods - Maintaining sterile environment - Environmental monitoring - Pre-analytical phase roles Sterile technique in the lab Sterile technique principles, Hand hygiene practices, PPE usage, Sterilization methods, Maintaining sterile environment, Environmental monitoring, Pre-analytical phase roles 2026-06-30 2026-06-30 The Biomedical & Life Sciences Collection https://hstalks.com/t/18275/pediatric-research-technical-logistical-considerat/?biosci Pediatric research rationale - American Academy of Pediatrics guidelines (1995) - ADME summary - Post natal ontogeny: Additional dynamics - Post natal ontogeny medicinal product dosing implications - Dosing approaches - Body surface and weight-based dosing - Age-based dosing: Approximations that require careful monitoring - General pediatric dosing considerations - Dosage forms Pediatric research: technical & logistical considerations - post natal ontogeny Prof. Steven Hirschfeld Pediatric research rationale, American Academy of Pediatrics guidelines (1995), ADME summary, Post natal ontogeny: Additional dynamics, Post natal ontogeny medicinal product dosing implications, Dosing approaches, Body surface and weight-based dosing, Age-based dosing: Approximations that require careful monitoring, General pediatric dosing considerations, Dosage forms 2026-05-28 2026-05-28 The Biomedical & Life Sciences Collection https://hstalks.com/t/21774/pharmaceutical-biotechnology/?biosci Pharmaceutical biotech advances - Biologic drug development - Large-scale production breakthroughs - Biologic manufacturing complexities - Biologic stability and immune challenges - Biosimilars and gene editing solutions - Regulatory landscape and impact Pharmaceutical biotechnology Pharmaceutical biotech advances, Biologic drug development, Large-scale production breakthroughs, Biologic manufacturing complexities, Biologic stability and immune challenges, Biosimilars and gene editing solutions, Regulatory landscape and impact 2026-05-28 2026-05-28 The Biomedical & Life Sciences Collection https://hstalks.com/t/21778/cholesterol-biosynthesis-and-statins/?biosci Cholesterol biosynthesis pathway - Regulation of hepatic cholesterol - Statin mechanism of action - Statin clinical uses and benefits - Statin side effects and monitoring Cholesterol biosynthesis and statins Cholesterol biosynthesis pathway, Regulation of hepatic cholesterol, Statin mechanism of action, Statin clinical uses and benefits, Statin side effects and monitoring 2026-05-28 2026-05-28 The Biomedical & Life Sciences Collection https://hstalks.com/t/21096/kalihinol-analog-med6-189-a-promising-pan-antimala/?biosci Antimalarial drug discovery - Natural product analogues (Kalinol) - Drug-resistant Plasmodium falciparum - Mechanism of action studies - Apicoplast targeting - Vesicular trafficking pathways - Semi-synthetic compound (MED6-189) - Preclinical development and translational challenges Kalihinol analog MED6-189: a promising pan-antimalarial candidate Prof. Karine Le Roch Antimalarial drug discovery, Natural product analogues (Kalinol), Drug-resistant Plasmodium falciparum, Mechanism of action studies, Apicoplast targeting, Vesicular trafficking pathways, Semi-synthetic compound (MED6-189), Preclinical development and translational challenges 2026-05-28 2026-05-28 The Biomedical & Life Sciences Collection