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Navigable Slide Index

1. Introduction
2. Ischemic stroke
3. Hypoxia-ischemia brain injury
4. Loss of ATP and brain function
5. Cytotoxic edema
6. Aquaporins and cerebral edema during stroke
7. Role of astrocytes during ischemia
8. Brain edema during stroke: vasogenic
9. Morphologic features of BBB
10. BBB and cerbral endothelial cell transport pathway
11. Altered BBB morphologic features during ischemia
12. Role of actin in BBB permeability regulation
13. Mediators of cerebral edema
14. Reperfusion injury
15. Role of ROS in ischemic brain injury
16. ROS and reperfusion injury
17. Oxidative damage during hypoxia-ischemia injury
18. Oxidative damage during reperfusion injury
19. Antioxidant defense systems
20. SOD in stroke
21. Hemodynamic changes and BBB permeability
22. Hydrostatic brain edema
23. Hemorrhagic transformation
24. Tissue plasminogen activator
25. tPA and BBB disruption in stroke
26. Hyperglycemic stroke and the BBB
27. Summary
28. Acknowledgements

Topics Covered

• Ischemic brain injury
• Cytotoxic and vasogenic brain edema
• Role of BBB in brain edema during stroke
• Cellular regulation of BBB permeability
• Reperfusion injury
• Oxidative damage
• Aquaporins and brain edema
• Mediators of brain edema
• Hemodynamic change during stroke

Links

Series:

• The Blood-Brain Barrier

Categories:

• Clinical Practice
• Neuroscience

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on March 1, 2008
• Archived on May 31, 2018

Financial Disclosures

• Prof. Marilyn Cipolla has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.