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Navigable Slide Index

1. Introduction
2. Talk outline
3. Population-based analysis
4. Contingency table in case-control analysis (1)
5. Contingency table in case-control analysis (2)
6. Cochran-Armitage test
7. Qualitative and quantitative trait
8. Population stratification
9. The population stratification problem
10. Solution for the population stratification problem
11. Methods for dealing with the problem
12. Genomic control (GC)
13. Structure analysis (SA)
14. Principal component analysis (1)
15. Principal component analysis (2)
16. Comparison between methods (1)
17. Comparison between methods (2)
18. Comparison in terms of statistical power
19. Family-based analysis
20. TDT
21. Example for calculation of TDT statistics
22. Properties of TDT
23. Independent transmissions between affected sibs
24. Extension of TDT
25. Dealing with missing parental genotypes
26. Several characteristics for family-based designs (1)
27. POO effects (1)
28. POO effects (2)
29. Several characteristics for family-based designs (2)
30. Comparing designs in terms of statistical power (1)
31. Comparing designs in terms of statistical power (2)
32. Comparing designs in terms of statistical power (3)
33. Comparing the designs in terms of cost and time
34. Comparison in the presence of genotyping errors
35. Genome-wide association analysis
36. Multiple stage design
37. Multiple stage design for case-control analysis
38. Multiple stage design for family-based analysis
39. Combine two designs
40. Combine two tests
41. Conclusions (1)
42. Conclusions (2)
43. References

Topics Covered

• Population-based association analysis
• Population stratification
• Genomic control
• Structure analysis
• Principal component analysis
• Family-based association analysis
• Parent-of-origin effect
• Genome-wide association analysis
• Combined test using family and population data

Links

Series:

• Genetic Epidemiology II

Categories:

• Genetics & Epigenetics
• Methods

Talk Citation

Chung, R. (2007, October 1). Choosing between family-based and population-based association designs [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 19, 2024, from https://hstalks.com/bs/604/.
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Publication History

• Published on October 1, 2007
• Archived on February 25, 2021

Financial Disclosures

• Dr. Ren-Hua Chung has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.