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Navigable Slide Index

1. Introduction
2. Ca2+ signal generation
3. Ca2+ release from internal stores
4. The discovery of intracellular Ca2+ release
5. Effect of ACh and adrenaline on Ca2+ release
6. Effect of intracellular Ca2+ injection
7. Ca2+ - mediated agonist-elicited channel opening
8. Techniques used in studying Ca2+ signaling
9. ACh elicits repetitive Ca2+ spikes through IP3Rs
10. Ach causes repetitive release of Ca2+ from ER
11. ACh elicits IP3 formation, IP3 releases Ca2+
12. ER penetrates into granular pole, where IP3Rs are
13. cADPR and NAADP also elicit local Ca2+ spikes
14. CCK action is dependent on NAADP receptors
15. Local/global Ca2+ oscillations in intact pancreas
16. Globalisation of Ca2+ signal
17. Summary of part 1
18. Ca2+-dependent release of NO
19. Ca2+ release by supramaximal ACh stimulation
20. The ER is a functional Ca2+ tunnel (1)
21. The ER is a functional Ca2+ tunnel (2)
22. The mitochondrial Ca2+ buffer barrier
23. The secretory granules - another Ca2+ store
24. Ca2+ in ER and non-ER stores
25. Ca2+ release from granules
26. Ca2+ signal generation in the apical granular pole
27. Summary of Ca2+ signaling events

Topics Covered

• Calcium release from intracellular stores as opposed to Calcium entry from the external solution
• The pioneers of Calcium signaling
• Patch clamp recording combined with optical Calcium measurements
• Calcium measurements in various organelles
• Different Calcium releasing messengers
• Calcium-mediated NO release
• Calcium tunnels
• Stimulusmetabolism coupling
• Calcium release from the endoplasmic reticulum and from acid stores
• Local and global Calcium signaling also in the intact tissue

Links

Series:

• Calcium Signaling I

Categories:

• Biochemistry
• Cell Biology

Talk Citation

Petersen, O. (2007, October 1). Coordinated Ca2+ release from intracellular Ca2+ stores [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 19, 2024, from https://hstalks.com/bs/407/.
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Publication History

• Published on October 1, 2007
• Archived on February 25, 2021

Financial Disclosures

• Prof. Ole Petersen has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.