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- Perspective and Pathogenesis
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1. Expanding frontiers of cerebrovascular disease
- Prof. Vladimir Hachinski
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2. Basic anatomy, physiology and pathophysiology of the cerebral circulation for the physician
- Prof. Jean-Claude Baron
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3. Pathophysiology of cerebral ischemia
- Prof. Wolf-Dieter Heiss
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4. Intracerebral hemorrhages: causes and clinical findings
- Prof. Louis Caplan
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5. Subarachnoid hemorrhage (SAH)
- Prof. R. Loch Macdonald
- Diagnosis
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6. Clinical diagnosis of stroke and subtypes
- Prof. Louis Caplan
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7. The investigation of stroke
- Dr. Bart Demaerschalk
- Treatment
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8. Acute therapy of stroke and reperfusion treatments
- Prof. Brian Silver
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9. Subarachnoid hemorrhage diagnosis and management
- Prof. Gary K. Steinberg
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10. Stroke-induced heart injury
- Dr. Luciano A. Sposato
- Rehabilitation
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11. Stroke rehabilitation: principles of stroke
- Prof. Robert Teasell
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12. Stroke rehabilitation: therapies and treatments
- Prof. Robert Teasell
- Prevention
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13. Lifestyle and nutrition in stroke prevention
- Prof. J. David Spence
- Special Topics
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15. Pediatric stroke: cerebrovascular injury in the developing brain
- Prof. Adam Kirton
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16. Stroke in women: epidemiology, risk and prevention
- Prof. Cheryl Bushnell
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17. Transient ischemic attack and cognition
- Dr. Jennifer Mandzia
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18. Vascular cognitive impairment
- Prof. Eric E. Smith
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19. Atrial fibrillation, anticoagulation and vitamins for homocysteine
- Prof. J. David Spence
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20. Stroke in the young adult
- Prof. Jeffrey Saver
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21. Stroke in the young
- Dr. Gyan Kumar
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22. Convergence and joint prevention of stroke and dementia
- Prof. Vladimir Hachinski
- Archived Lectures *These may not cover the latest advances in the field
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23. Vascular cognitive impairment
- Dr. John Bowler
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24. Pediatric stroke
- Dr. Gabrielle deVeber
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25. The deteriorating stroke
- Prof. Werner Hacke
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26. General management
- Prof. Bo Norrving
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27. The treatment of stroke: specific management - thrombolysis plus
- Prof. Nils Wahlgren
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28. Rehabilitation: the chronic phase
- Prof. Lalit Kalra
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29. Prevention: management of risk and protective factors
- Prof. Graeme Hankey
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30. Medical therapy for secondary prevention of ischemic stroke
- Prof. Larry Goldstein
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31. Subarachnoid haemorrhage
- Prof. Jan van Gijn
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32. Controversies in stroke
- Prof. Stephen Davies
- Prof. Geoffrey Donnan
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33. Medical and surgical stroke
- Prof. Carlos Kase
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34. The urgency of stroke prevention after TIA
- Prof. S. Claiborne Johnston
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35. Carotid endarterectomy, angioplasty and stenting
- Prof. Martin Brown
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36. The clinical diagnosis of stroke and stroke subtypes
- Prof. Louis Caplan
Printable Handouts
Navigable Slide Index
- Introduction
- Young Stroke
- Mortality
- Age
- Gender differences
- Race
- Risk factors
- Etiology
- Etiology (2)
- Cervical artery dissection (CAD)
- Pathogenesis of CAD
- CAD studies
- “Other determined” etiologies
- Patent Foramen Ovale (PFO)
- PFO RoPE
- PFO RoPE scores
- Randomized trials of PFO closure and meta-analysis
- PFO RCT Results
- PFO closure
- Screening for PFO
- Criteria for PFO Closure
- Cryptogenic ischemic strokes
- Etiologic workup
- Further testing
- Acute Reperfusion Therapy
- Secondary prevention
- Thank you
Topics Covered
- Scope and epidemiology of stroke in the young
- Risk factors and etiology
- TOAST classification
- Cervical artery dissection
- Primary hypercoagulable states and other determined etiologies
- Patent foramen ovale
- RoPE score
- Overlap between young stroke and cryptogenic stroke
- Reperfusion therapy and secondary prevention
Links
Series:
Categories:
Therapeutic Areas:
External Links
Talk Citation
Kumar, G. (2021, March 30). Stroke in the young [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 31, 2024, from https://doi.org/10.69645/JZXA6483.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Gyan Kumar has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
A selection of talks on Neurology
Transcript
Please wait while the transcript is being prepared...
0:00
Hi, I'm Gyan Kumar,
I'm a stroke neurologist at the Mayo Clinic in Arizona.
In this talk, I'll talk about stroke in the young population.
0:10
Approximately 10 percent of ischemic stroke occurs in the young population.
Although there is some variability across
studies in the age cut-off for defining young stroke,
generally, stroke in an individual younger than 55 years of age is labeled 'young stroke'.
This talk focuses on ischemic stroke affecting young adults over 18 years of age.
0:32
Population and hospital-based registry data have shown that young people who suffer
strokes have a mortality risk that is five-fold, compared to the general population.
0:44
Incidence of ischemic stroke has steadily
declined in the older population over the past two decades.
In contrast, incidence is rising in young adults,
as shown by population-based studies.
There has been a decrease in the average age at stroke onset in the young that is
attributable to an increase in the incidence of stroke in this population.
This is also contrary to trends seen with other diseases.
This increase in incidence coupled with a decrease in age at
onset is illustrated by findings from these studies:
a study of nationwide inpatient sample data showed
that the incidence of ischemic stroke hospitalizations rose
from 28 to 38 per 10,000 hospitalizations, over the period of a decade from 1997-2007;
the Greater Cincinnati/Northern Kentucky Stroke Study showed that the proportion of strokes in
the young rose from 13 percent to 19 percent in just over a decade,
while mean age of stroke onset fell from 71 to 69 years;
the Danish registry showed that hospitalizations for ischemic stroke rose from
12 to 17 per 100,000 patient years over a period of just under two decades,
this increase was more pronounced in the recent years;