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1. Introduction
2. Messages
3. Talk outline
4. Exocytosis
5. The forms life
6. Inventions after emergence of eukaryotic cells
7. Development of eumetazoans
8. Neuromuscular junction and secretory organelles
9. Release of neural transmitter substances
10. Classical view of exocytosis in neurons
11. The patch-clamp monitoring
12. The patch-clamp monitoring used on a neuron
13. Fastest rate constant of vesicle fusion in neurons
14. The patch-clamp monitoring used on an astrocyte
15. Microinjection of tetanus toxin to astrocytes
16. Tetanus toxin and vesicle fusion in astrocytes
17. Rate constant of vesicle fusion in astrocytes
18. Regulated exocytosis and gliotransmission
19. Simultaneous measurements of cell swelling
20. Exocytosis in astrocytes
21. Types of vesicles in astrocytes
22. Glutamate (Glu) release from astrocytes
23. Glu release & measurements of NADH and Cm
24. Calcium-dependent release of peptides
25. Peptide-containing vesicles appear to store ATP
26. Studying ATP release from astrocytes
27. Slow transient inward current
28. STICs occur in a calcium-dependent manner
29. Conclusions
30. Acknowledgements

Topics Covered

• Exocytosis
• Exocytosis in evolution
• Exocytosis in astrocytes
• Development of eumetazoans
• Neuromuscular junction and secretory organelles
• The patch-clamp monitoring of membrane capacitance (surface area) in cultured neurones and astrocytes
• Simultaneous measurements of cell swelling by monitoring cell cross section area and membrane capacitance
• Astrocytes exhibit calcium-dependent regulated exocytosis
• Glutamate release from astrocytes
• Calcium-dependent release of peptides

Links

Series:

• Physiology and Pathophysiology of Neuroglia

Categories:

• Cell Biology
• Neuroscience

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on June 29, 2011

Financial Disclosures

• There are no commercial/financial disclosures.