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1. Introduction
2. Video capillaroscopy
3. Analysis with capillaroscopy (1)
4. Analysis with capillaroscopy (2)
5. Analysis with capillaroscopy (3)
6. Analysis with capillaroscopy (4)
7. Analysis with capillaroscopy (5)
8. Analysis with capillaroscopy (6)
9. Lens ability to evaluate vessel network
10. Limit of detection
11. Nailfold vascular bed
12. Analysis of healthy subject
13. Raynaud's phenomenon and role of capillaroscopy
14. Mechanisms contributing to RP
15. Physical features of Raynaud's phenomenon
16. Normal response to cold challenge in PRP
17. Acute phase of primary Raynaud's phenomenon
18. RP response to cold challenge in SRP
19. Scleroderma
20. Patophysiology of scleroderma
21. Lesions observed in the nailfolds
22. Lesions observed in the skin
23. Early clinical signs
24. Classification of the SSc patterns
25. Infiltration of immune cells around vessels
26. Megacapillaries
27. Megacapillaries and edema
28. Microhaemorrages
29. Capillaroscopic patterns in SSc - early phase
30. Changes in capillaries
31. Capillaroscopic patterns in SSc - active phase
32. Production of extra-cellular matrix proteins
33. Necrotic lesions on the skin
34. Fibrosis
35. Neoangiogenesis
36. Fibrosis and neoangiogenesis
37. Late pattern - loss of capillaries
38. Capillaroscopic patterns in SSc - late phase
39. Capillaroscopic patterns in scleroderma: summary
40. Dermatomyiositis
41. Dermatomyiositis - capillary abnormalities
42. Systemic lupus erythematosus
43. SLE - capillary abnormalities
44. Antiphospholipid syndrome
45. APL syndrome - capillary abnormalities
46. Impaired cerebral blood flow in SSc patients
47. Blood flow in the brain in slceroderma
48. Cerebral hypoperfusion in SSc patients
49. Cerebral blood flow in SSc patients
50. Cyclosporin treatment of SSc
51. Capillaroscopy during cyclosporin treatment
52. Endothelin contributes to RP
53. High levels of ET are present in RP
54. High levels of ET are present in late stage of SSc
55. Endothelin levels in the different patterns
56. Fibronectin synthesis
57. Endothelin activates damage progression
58. Acknowledgments
59. 1st European course of capillaroscopy
60. 2nd European course of capillaroscopy

Topics Covered

• Materials and methods for the correct employment of the video capillaroscopy
• The Raynaud's phenomenon and the role of capillaroscopy
• The scleroderma pattern today
• Scleroderma pattern and pathophysiological significance
• Frequent patterns in dermatomyositis, systemic lupus erythematosus and antiphospholipid syndromes
• Correlations between the capillaroscopic patterns and clinical and laboratory findings

Links

Series:

• Autoimmunity

Categories:

• Clinical Practice
• Immunology

Therapeutic Areas:

• Immunology & Inflammation

Talk Citation

Publication History

• Published on October 1, 2007

Financial Disclosures

• Prof. Maurizio Cutolo has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.