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Talk: Optical imaging in biomedicine (30 min)

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X Navigable Slide Index
  1. Introduction
  2. What is biophotonics?
  3. Why use biophotonics?
  4. Need for biophotonics in medicine
  5. Photomedicine in cancer
  6. In vivo optical imaging in cancer
  7. Research in nano-biophotonics
  8. Endoscopic optical biopsy
  9. Hypericin - a novel photosensitizer
  10. Real-time fluorescence diagnostic system (1)
  11. Real-time fluorescence diagnostic system (2)
  12. Macrosocopic fluorescence imaging with hypericin
  13. White light and fluorescence of oral lesions
  14. Image analysis algorithm
  15. Diagnostic accuracy of cancer detection
  16. Macroscopic fluorescence analysis
  17. Microscopic fluorescence analysis
  18. Fluorescence cytology images in hypericin ex-vivo
  19. Ex-vivo optical methods
  20. Endoscopic autofluorescence imaging
  21. Optimal excitation/emission wavelengths
  22. Autofluorescence lifetime studies
  23. Towards a 3D fluorescence diagnostic system
  24. Laser confocal endomicroscope
  25. The novel rigid confocal endomicroscope system
  26. In-vivo cellular confocal endomicroscopy
  27. Extension to a 3D system
  28. Ex-vivo imaging of the mouse tongue
  29. Clinical laser confocal endomicroscope
  30. Optical coherence tomography (OCT)
  31. OCT vs. confocal imaging
  32. OCT images of the eye
  33. Optical coherence tomography in NCC
  34. OCT image of subcutaneous tumour
  35. Oncological applications in OCT
  36. OCT-MEMS scanning mirror technology
  37. Patented MEMS probe technology
  38. Nano-oncology
  39. Nano conjugated biomarkers to image cancer cells
  40. Metallic nanostructures as contrast agents
  41. Gold nanoshells in cancer imaging and therapy
  42. Gold nanoshell and nanorod antennas
  43. Combine structural and molecular imaging
  44. Bioconjugated gold nanoshells as contrast agents
  45. Raman spectroscopy
  46. Surface enhanced Raman spectroscopy (SERS)
  47. Intensity comparison of Au NP and QD705
  48. Applications of SERS
  49. SERS tags for cellular targeting and quantification
  50. In vivo cancer targeting using SERS
  51. A fiber optic probe with SERS-nanoparticle
  52. SERS microfluidic method for ex-vivo bio-sensing
  53. SERS bio-sensing
  54. Acknowledgements
  55. END
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DETAILED SLIDE INDEX

  1. 1. Introduction
  2. 2. What is biophotonics?
  3. 3. Why use biophotonics?
  4. 4. Need for biophotonics in medicine
  5. 5. Photomedicine in cancer
  6. 6. In vivo optical imaging in cancer
  7. 7. Research in nano-biophotonics
  8. 8. Endoscopic optical biopsy
  9. 9. Hypericin - a novel photosensitizer
  10. 10. Real-time fluorescence diagnostic system (1)
  11. 11. Real-time fluorescence diagnostic system (2)
  12. 12. Macrosocopic fluorescence imaging with hypericin
  13. 13. White light and fluorescence of oral lesions
  14. 14. Image analysis algorithm
  15. 15. Diagnostic accuracy of cancer detection
  16. 16. Macroscopic fluorescence analysis
  17. 17. Microscopic fluorescence analysis
  18. 18. Fluorescence cytology images in hypericin ex-vivo
  19. 19. Ex-vivo optical methods
  20. 20. Endoscopic autofluorescence imaging
  21. 21. Optimal excitation/emission wavelengths
  22. 22. Autofluorescence lifetime studies
  23. 23. Towards a 3D fluorescence diagnostic system
  24. 24. Laser confocal endomicroscope
  25. 25. The novel rigid confocal endomicroscope system
  26. 26. In-vivo cellular confocal endomicroscopy
  27. 27. Extension to a 3D system
  28. 28. Ex-vivo imaging of the mouse tongue
  29. 29. Clinical laser confocal endomicroscope
  30. 30. Optical coherence tomography (OCT)
  31. 31. OCT vs. confocal imaging
  32. 32. OCT images of the eye
  33. 33. Optical coherence tomography in NCC
  34. 34. OCT image of subcutaneous tumour
  35. 35. Oncological applications in OCT
  36. 36. OCT-MEMS scanning mirror technology
  37. 37. Patented MEMS probe technology
  38. 38. Nano-oncology
  39. 39. Nano conjugated biomarkers to image cancer cells
  40. 40. Metallic nanostructures as contrast agents
  41. 41. Gold nanoshells in cancer imaging and therapy
  42. 42. Gold nanoshell and nanorod antennas
  43. 43. Combine structural and molecular imaging
  44. 44. Bioconjugated gold nanoshells as contrast agents
  45. 45. Raman spectroscopy
  46. 46. Surface enhanced Raman spectroscopy (SERS)
  47. 47. Intensity comparison of Au NP and QD705
  48. 48. Applications of SERS
  49. 49. SERS tags for cellular targeting and quantification
  50. 50. In vivo cancer targeting using SERS
  51. 51. A fiber optic probe with SERS-nanoparticle
  52. 52. SERS microfluidic method for ex-vivo bio-sensing
  53. 53. SERS bio-sensing
  54. 54. Acknowledgements
  55. 55. END

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TALK'S CITATION

Olivo, M. (2010), "Optical imaging in biomedicine", in Townsend, D. (ed.), Medical Imaging: Imaging Techniques for Pre-clinical and Clinical Applications, The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London (online at http://hstalks.com/?t=BL1032775)

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ABOUT THIS TALK

Speaker(s)

Prof. Malini Olivo Show Biography

SPEAKER BIOGRAPHY

Prof. Malini Olivo – National University of Ireland, Galway, Ireland

Malini Olivo is the SFI Stokes Professor of Biophotonics in the School of Physics at the National University of Ireland, Galway, as well as an Adjunct Professor at the National University of Singapore. She received her BSc from the University of Malaya and PhD in biomedical physics from University College London. Prof. Malini Olivo is a pioneer in the area of clinical applications of photomedicine in optical photodiagnostics and Phototherapeutics. The focus of her laboratory is to investigate minimally invasive novel optical methods for cancer detection and therapy using biophotonics and nanotechnology.

Publication Date

September, 2010

Topics Covered

What is biophotonics?... more

TOPICS COVERED IN THIS TALK

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  • Photomedicine in cancer
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  • Image analysis algorithm
  • Diagnostic accuracy of bladder and oral cancer detection using fluorescence
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  • Ex-vivo optical methods
  • Autofluorescence lifetime studies
  • Towards a 3D fluorescence in vivo cellular diagnostic system
  • Optical coherence tomography (OCT)
  • OCT vs. confocal imaging
  • Nano-oncology
  • Nano-based imaging
  • Nano-drug delivery systems

Series

Medical Imaging

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