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Printable Handouts
Navigable Slide Index
- Introduction
- Outline of the talk
- Aim & scope
- R environment for statistical analysis
- Rationale of R for genetic data
- R packages for genetic data
- Installation and use of package(s)
- Summary of an imaginary data
- Test of Hardy-Weinberg equilibrium
- Haplotype analysis
- Pedigree-drawing
- Regional association
- Example: the Framingham data
- GenABEL: identity-by-state (IBS) statistics
- GenABEL: polygenic model
- Q-Q and Manhattan plots
- To recap: GWAS
- Issues and challenges
- Meta-analysis
- Use of publicly available data
- A technical summary
- A general perspective
- Further readings
Topics Covered
- R environment for statistical analysis
- Rationale of R for genetic data
- Use of packages
- Haplotype analysis
- Regional association
- The Framingham data
- GenABEL
- Q-Q and Manhattan plots
- GWAS
- Issues and challenges
- Meta-analysis
- Use of publically available data
- A technical summary
Talk Citation
Zhao, J.H. (2009, September 10). Genetic association analysis with R [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved August 31, 2024, from https://doi.org/10.69645/DCRY5578.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Jing Hua Zhao has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.