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|Speakers||Prof. Brian Druker – Oregon Health & Science University Cancer Institute, USA|
Signal Transduction via Protein Tyrosine Kinase Receptors|
|...of Leukemia Research at Oregon Health & Science University (OHSU) Cancer Institute. ... more|
Dr. Druker's research focuses on the regulation of the growth of cancer cells and the practical application of this knowledge to cancer therapies. His laboratory performed critical pre-clinical studies of Gleevec (imatinib) that targets the molecular defect in chronic myeloid leukemia (CML). Dr. Druker then led the highly successful clinical trials of imatinib, which is now FDA approved for CML and gastrointestinal stromal tumors (GIST). He graduated from the University of California, San Diego School of Medicine in 1981, completed his internship and residency in internal medicine at Barnes Hospital, Washington School of Medicine, and then trained in oncology at the Dana-Farber Cancer Institute. He is now an Investigator of the Howard Hughes Medical Institute and JELD-WEN Chair of Leukemia Research at Oregon Health & Science University (OHSU) Cancer Institute.
Dr. David Barker is a physician and researcher. In 1989, with colleagues at the MRC Unit, University of Southampton, he discovered the relationship between birth weight and the lifetime risk for coronary heart disease. This led to the "Fetal Origins Hypothesis" which proposes that coronary heart disease originates through responses to under nutrition during fetal life and infancy, which permanently change the body's structure, physiology and metabolism. David Barker has published more than 200 papers and written or edited 5 books about the developmental origins of chronic disease. His recent findings have shown that a woman's diet at the time of conception and during pregnancy have important effects on the subsequent health of her offspring.
|Speakers||Prof. Jeffrey Hansen – Colorado State University, USA|
From DNA to Proteins|
|...in 1986, and was an NIH postdoctoral fellow at Oregon State University from 1987-1990. He spent 12 years... on the faculty of the University of Texas Health Science Center at San Antonio prior to moving... more|
Jeffrey Hansen is a Professor in the Department of Biochemistry and Molecular Biology at Colorado State University. He obtained his PhD in biochemistry from the University of Wisconsin-Madison in 1986, and was an NIH postdoctoral fellow at Oregon State University from 1987-1990. He spent 12 years on the faculty of the University of Texas Health Science Center at San Antonio prior to moving to Colorado State University in 2003. Over the last decade he has helped pioneer the use of analytical ultracentrifugation for studying complex macromolecular assemblages in solution. His research program focuses on biochemical and biophysical characterization of genome architecture.
Brad Cairns is an Associate Professor of Oncological Sciences in the Hunstman Cancer Institute at the University of Utah School of Medicine. He is also an Investigator with the Howard Hughes Medical Institute. Prof. Cairns received his Bachelor of Science degree in Chemistry from Lewis and Clark College in 1987, and then spent a year working in molecular parasitology with Scott Landfear at the Oregon Health Sciences University. In 1995, he received his PhD in Cell Biology from Stanford University, where he worked with Roger Kornberg on MAP kinase signaling and chromatin remodeling complexes. Prof. Cairns then worked with Fred Winston in the Department of Genetics at Harvard Medical School, where he pursued genetic and molecular analyses of chromatin remodeling. He joined the faculty at Utah in 1998, and HHMI in 2000. His laboratory utilizes biochemical, molecular, genetic and genomic approaches to understand how chromatin helps regulate gene expression.