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Natural Killer Cell Biology: Natural killer cell-mediated immunity to pathogens and cancer
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Natural Killer Cell Biology - sample extracts available

Natural Killer Cell Biology:

Natural killer cell-mediated immunity to pathogens and cancer

    TARGET AUDIENCE

For all those wishing to be briefed on the fundamentals and the latest developments in the study and understanding of NK cell biology including academics, physicians, and health personnel working in the areas of cancer, transplantation, infectious disease and immunotherapy, students at the undergraduate, graduate, and postgraduate levels working in the general area of immunology, as well as scientists in biotech or pharma involved in the development and manufacture of immunostimulatory drugs or vaccines for infectious diseases and cancer or in the area of immunosuppressive drugs for transplantation.


    SERIES EDITOR(S)

Prof. Lewis Lanier - University of California, San Francisco, USA

Lewis Lanier is an American Cancer Society Research Professor and Professor and Vice Chair, Department of Microbiology & Immunology at the University of California, San Francisco, USA. His laboratory research focuses on the human and mouse activating and inhibitory receptors that are predominantly expressed by Natural Killer (NK) cells, but are also present on subsets of effector/memory T cells and some myeloid cells. He is particularly interested in the activating NK receptors that signal by associating with two distinct signaling adapter proteins named DAP10 and DAP12. The goal of his research is to understand the role of these NK cell receptors in immune defense against tumors and microbial pathogens, and explore their potential detrimental role in autoimmune diseases.


Series Online Publication: Sep 2009



     How Natural Killer Cells Recognize Self

Education and tuning of natural killer cells - play sample talk extractEducation and tuning of natural killer cells - view talk information

1. Education and tuning of natural killer cells (53 mins)
Prof. Eric Vivier - Centre d'Immunologie de Marseille-Luminy, France
Dr. Sophie Ugolini - Centre d'Immunologie de Marseille-Luminy, France

Disarming of autoreactive NK cells - play sample talk extractDisarming of autoreactive NK cells - view talk information

2. Disarming of autoreactive NK cells (46 mins)
Prof. David Raulet - University of California, Berkeley, USA

     Development and Function of Natural Killer Cell Subsets

Natural killer cell development - play sample talk extractNatural killer cell development - view talk information

3. Natural killer cell development (23 mins)
Dr. Francesco Colucci - Babraham Institute, University of Cambridge, UK

NK cells in viral immunity - play sample talk extractNK cells in viral immunity - view talk information

5. NK cells in viral immunity (38 mins)
Prof. Lewis Lanier - University of California, San Francisco, USA

NK cell subsets and interactions with dendritic cells - play sample talk extractNK cell subsets and interactions with dendritic cells - view talk information

6. NK cell subsets and interactions with dendritic cells (58 mins)
Prof. Christian Münz - University of Zurich, Switzerland

Immunodeficiencies and genetic mutations affecting NK cells in humans - play sample talk extractImmunodeficiencies and genetic mutations affecting NK cells in humans - view talk information

7. Immunodeficiencies and genetic mutations affecting NK cells in humans (53 mins)
Dr. Jordan Orange - Children’s Hospital of Philadelphia, USA

     Natural Killer Cell Receptors and Signaling

Evolution of NK cell receptors - play sample talk extractEvolution of NK cell receptors - view talk information

8. Evolution of NK cell receptors (42 mins)
Prof. John Trowsdale - University of Cambridge, UK