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Signal Transduction via Protein Tyrosine Kinase Receptors:
Structures, Function, Regulation, Mechanisms and Role in Disease
For everyone wishing to be kept abreast of the latest developments in this rapidly advancing field including: Students and post-doctoral researchers in cell biology, biochemistry, developmental biology and cancer, and pharmaceutical researchers investigating low molecular weight inhibitors for PTK receptors.
Prof. Carl-Henrik Heldin - Ludwig Institute of Cancer Research, Sweden
C.-H. Heldin is since 1986 the Branch Director of the Ludwig Institute for Cancer Research in Uppsala, Sweden, and since 1992 also professor in Molecular Cell Biology at Uppsala University. He was born in 1952, and obtained a PhD degree in Medical and Physiological Chemistry in 1980 at the University of Uppsala, where he continued to work until 1985 using a position sponsored by the Swedish Cancer Society. The research interest of C.-H. Heldin is related to the mechanisms of signal transduction by growth regulatory factors, as well as their normal function and role in disease. In particular, platelet-derived growth factor (PDGF), a major mitogen for connective tissue cells, and transforming growth factor beta (TGF beta), which inhibits the growth of most cell types, are studied. An important goal is to explore the possible clinical utility of signal transduction antagonists.
Series Online Publication: Oct 2007
Function of important examples of PTK receptor families
Structure of PTK receptors and regulation of their kinases
Negative regulation of PTK receptors
Intracellular signal transduction by PTK receptors
Clinical use of PTK receptor antagonists
Latest Developments in the Field
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