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> Home / Biomedical & Life Sciences / Series / The Legacy of Drosophila Genetics

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The Legacy of Drosophila Genetics: From 'defining the gene' to 'analyzing genome function'

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The Legacy of Drosophila Genetics:

From 'defining the gene' to 'analyzing genome function'

TARGET AUDIENCE

For all those wishing to be briefed on the latest developments in the study and understanding of Drosophila genetics including upper division undergraduate students majoring in biology, graduate students in biology, bioinformatics and biochemistry, and medical students, researchers in academic departments needing to be kept abreast of the latest developments in these areas and researchers in pharmaceutical companies investigating the genetic basis of disease.

SERIES EDITOR(S)

Prof. Ethan Bier - Section of Cell and Developmental Biology, University of California, San Diego, USA

Ethan Bier’s laboratory at the University of California, San Diego studies the genetic control of development in Drosophila, focusing on how morphogen gradients establish cell fates along the dorsal-ventral axis and on how sharp lines form between adjacent territories of cells. His group is also interested in using fruit flies to study the mechanistic basis for human disease gene action. Dr. Bier received his undergraduate training at the University of California, San Diego, pursued his graduate work with Dr. Alan Maxam at Harvard Medical School, and then his postdoctoral studies with Drs. Lily and Yuh-Nung Jan at the University of California, San Francisco

Series Online Publication: Sep 2008

Introduction

1. Drosophila genetics - the first 25 years (63 mins)
Prof. Dan Lindsley - University of California, San Diego, USA

Establishment of the Primary Body Axes

2. The homeotic genes of the bithorax complex in Drosophila (29 mins)
Prof. Francois Karch - University of Geneva, Switzerland

3. Regulation of gastrulation in Drosophila (49 mins)
Prof. Dr. Maria Leptin - University of Cologne, Germany

4. Limb development: how Drosophila genetics can be used to understand pattern formation (30 mins)
Prof. Konrad Basler - University of Zurich, Switzerland

Cell Type Specification and Organ Systems

5. microRNA function in stem cells (31 mins)
Prof. Hannele Ruohola-Baker - University of Washington, USA

6. From germ cell specification to gonad formation (63 mins)
Prof. Ruth Lehmann - New York University School of Medicine, USA

7. Drosophila stem cells (37 mins)
Dr. Michael Buszczak - University of Texas Southwestern Medical Center, USA

8. The miracle of morphogenesis, cell adhesion, polarity and cytoskeletal regulation (43 mins)
Prof. Mark Peifer - University of North Carolina at Chapel Hill, USA

9. Axon guidance in Drosophila (34 mins)
Prof. John Thomas - Salk Institute for Biological Studies, USA

10. Development and physiology of the heart (35 mins)
Prof. Rolf Bodmer - Burnham Institute for Biomedical Research, USA

Genome Organization and Function

11. The genetic analysis of meiosis in Drosophila melanogaster females (53 mins)
Prof. R. Scott Hawley - The Stowers Institute for Medical Research, USA

12. Genome scale analysis of cellular processes using RNAi (46 mins)
Dr. Amy Kiger - University of California, San Diego, USA

13. Dorsal-ventral patterning of the Drosophila embryo (37 mins)
Prof. Mike Levine - University of California, Berkeley, USA

14. Using gene expression information to provide insights into patterning and differentiation (25 mins)
Prof. Angelike Stathopoulos - California Institute of Technology, USA

Behavior

15. The development of the peripheral nervous system in the fruitfly Drosophila (40 mins)
Prof. Hugo Bellen - Baylor College of Medicine, USA

16. Genetics of chemosensory transduction: taste and smell (54 mins)
Dr. Leslie Vosshall - The Rockefeller University, USA

17. Cracking the case of circadian rhythms by Drosophila genetics (73 mins)
Prof. Jeffrey Hall - Brandeis University, USA

18. Sleep in Drosophila (46 mins)
Dr. Ralph Greenspan - The Neurosciences Institute, USA

19. Drosophila's contribution to the genetics of learning and memory (91 mins)
Prof. Tim Tully - Dart Neuroscience LLC, USA

20. Drosophila as a model for drug addiction (34 mins)
Prof. Ulrike Heberlein - University of California, San Francisco, USA

Mechanism of Human Disease

21. Cross-genomic analysis of human disease genes (65 mins)
Prof. Ethan Bier - University of California, San Diego, USA

22. Human neurodegenerative disease: insights from Drosophila genetics (56 mins)
Prof. Nancy Bonini - University of Pennsylvania and Howard Hughes Medical Institute, USA

23. Metastasis of Drosophila tumors (21 mins)
Prof. Allen Shearn - Professor Emeritus, Johns Hopkins University, USA

24. Control of tissue growth: elucidation of the Hippo signaling pathway (34 mins)
Dr. Duojia Pan - Johns Hopkins University School of Medicine, USA

Evolution of Adaptive Novelties

25. The evolution of morphological novelty (56 mins)
Prof. Nipam Patel - University of California, Berkeley and Howard Hughes Medical Institute, USA

26. The genetic architecture of complex traits: lessons from Drosophila (36 mins)
Prof. Trudy Mackay - North Carolina State University, USA