Browse list of available series in The Biomedical & Life Sciences Collection
Recommend The Biomedical & Life Sciences Collection to your librarian
Request to be kept updated on The Biomedical & Life Sciences Collection
Apply for a free trial of The Biomedical & Life Sciences Collection
View all talks & series with full access

Guest (sample access)

Optional Login with Username


        
> Home  /  Biomedical & Life Sciences  /  Series  /  Evolution and Medicine  /  Talk Details
SHARE:   Email via Outlook   Email via Web   Facebook   Twitter   |   more
Close SHARE
Please select one of the methods below to share the following page with your collegues:
Evolution: Medicine's Missing Basic Science
Blogger Google Reader
Delicious Linked In
Digg MySpace
Favorites PDF Online
Gmail

Hello. As a guest, you do not have full access to this talk. Click the PLAY button below to watch the sample extract. Alternatively, you may login or review methods of obtaining more access.

    SPEAKER(S)

Prof. Randolph Nesse - University of Michigan, USA

Randolph M. Nesse, MD, is Professor of Psychiatry and Professor of Psychology at the University of Michigan, where he directs the Evolution and Human Adaptation Program. He collaborated with George Williams to write several seminal works on Darwinian Medicine, including Why We Get Sick: The New Science of Darwinian Medicine. His early research on the neuroendocrinology of anxiety has been transformed into a focus on how selection shapes mechanisms that regulate defenses such as pain, fever, anxiety and low mood. He is devoted to the mission of helping to organize the growing Evolution and Medicine community via writing, speaking and EvolutionAndMedicine.org.

Talk Online Publication: Oct 2007

TOPICS COVERED IN EVOLUTION: MEDICINE'S MISSING BASIC SCIENCE

How evolution is useful to medicine - Why doctors don't know evolution - The body: perfect and pathetically flawed - Proximate and evolutionary explanations - Explain vulnerability, not diseases - Six reasons for vulnerability - Darwinian medicine growing fast

How to cite this talk:
Nesse, R. (2007), "Evolution: Medicine's Missing Basic Science", in Nesse, R. (ed.), Evolution and Medicine: How New Applications Advance Research and Practice, The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London (online at http://hstalks.com/bio)

Direct talk access link:
http://hstalks.com/lib.php?t=HST14.1449_1_3&c=252

    DETAILED SLIDE INDEX

1. Introduction
2. The goal of evolutionary/Darwinian medicine
3. Medicine uses some evolution
4. But much is missing
5. Some general principles
6. General principles corrected
7. Schools that include topic in medical curriculum
8. Evolutionary biology faculty in medical schools
9. Gertrude Stein on her deathbed
10. Volnerability of the body and natural selection
11. Natural selection is too weak to improve the body
12. The new answer
13. The dawn of Darwinian medicine
14. A picture of George Williams
15. Disease and evolution
16. An example: the eye
17. First half of medical school: an organ of perfection
18. In the clinic: a botched design
19. Designing a better body in one afternoon
20. Natural selection
21. Two kinds of explanation
22. Two complementary explanations
23. Tinbergen's 4 questions
24. Tinbergen's 4 questions organized
25. Four questions about honeycreeper beaks
26. The 30 cm spur of the star orchid and the moth
27. Darwinian medicine
28. How is evolution useful for medicine?
29. Direct applications in the clinic?
30. Evolution and medicine - branches
31. Why we get sick
32. Evolutionary questions about disease
33. Six reasons why diseases exist
34. 1. Mismatch
35. Atheroma
36. Cholesterol levels
37. Breast cancer
38. Genetic "quirks"
39. Myopia
40. Mean negative affect scores vs. BDNF genotype
41. Hygiene hypothesis
42. Signals of recent selection
43. BP, genes, latitude and environment
44. 2. Competition with other organisms
45. Streptococcal infection
46. Antibiotic resistance of 480 soil bacterial isolates
47. Virulence
48. 3. Every trait is a trade-off
49. Malaria in Melanesia
50. Alpha + thalassemia protects against malaria
51. Gout syndrome: uric acid crystals in joints
52. Billirubin: highly toxic compound, then why?
53. 4. Constraints
54. Terrestrial whales
55. Path dependence
56. 5. Health is not selection's goal
57. Senescence and pleiotropy
58. The strength of selection
59. Force of selection against senescence
60. If mortality stayed at early adulthood rates
61. The vulnerable sex
62. Male to female mortality ratio
63. Developmental pleiotropy a prediction
64. 6. Defenses and suffering
65. Charles Darwin
66. Defenses vs. defects
67. Defense regulation
68. The smoke detector principle (1)
69. What if the cue is unreliable?
70. How loud should the noise be before you run?
71. Optimal response threshold
72. Should you flee from a noise?
73. A threat and response
74. Being killed greatly decreases future fitness
75. Panic disorder
76. The smoke detector principle (2)
77. A phylogeny of emotions
78. A conclusion about defenses
79. Six reasons for vulnerability
80. Main conclusions
81. Some of many implications
82. Overall conclusion
83. The state of Darwinian medicine
84. www.EvolutionAndMedicine.org
85. END