Henry Stewart Talks

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Talks (146) Series (23)
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TALKS PUBLISHED/UPDATED IN THE LAST TWELVE MONTHS
May 2013
1. Update on therapies for metastatic melanoma (30 mins)
Play '1. Update on therapies for metastatic melanoma'
SpeakersDr. Vernon K. Sondak  –  H. Lee Moffitt Cancer Center and Research Institute, USA
Series Topical Talks
Relevant
    extract
Overview of new treatments approved for advanced melanoma in the past few years - Pegylated interferon alfa-2b - Ipilimumab - Mechanism of action - Impact on progression-free and overall survival -... more More info

April 2013
2. Innate immune receptors as mediators of systemic inflammation and pathogenesis of malaria (43 mins)
Play '2. Innate immune receptors as mediators of systemic inflammation and pathogenesis of malaria'
SpeakersProf. Ricardo Gazzinelli  –  University of Massachusetts Medical School, USA
Series Macrophage Heterogeneity and Function
Relevant
    extract
Malaria and Plasmodium parasites - Innate immune receptors - Plasmodium recognition by host innate immune receptors, and in particular by Toll-like Receptors (TLRs) - Excessive activation of TLRs a... more More info
3. Biomarkers for Alzheimer's disease (23 mins)
Play '3. Biomarkers for Alzheimer's disease'
SpeakersDr. Henrik Zetterberg  –  Gothenberg University, Sweden
Series Drug Discovery and Development in the Neurosciences
Biomarkers
Relevant
    extract
Biomarkers for Alzheimer's disease - What is Alzheimer's disease? - -The neuropathology of the disease -Biomarkers reflecting neuropathology - What is CSF? - Different uses of biomarkers - Clinical... more More info
4. Physiology of asthma and involvement of small airways (70 mins)
Play '4. Physiology of asthma and involvement of small airways'
SpeakersProf. Charles G. Irvin  –  University of Vermont, USA
Series Advances in Asthma
Relevant
    extract
Physiology of asthma, a syndrome defined by lung dysfunction - Airflow limitation - Small airways - Reversibility of airflow limitation - Periodicity and variability of airflow limitation - Airways... more More info

March 2013
5. Is there a role for academia in drug discovery (55 mins)
Play '5. Is there a role for academia in drug discovery'
SpeakersDr. Adrian J. Ivinson  –  Harvard Neurodiscovery Center, USA
Series Drug Discovery and Development in the Neurosciences
Relevant
    extract
Increasing numbers of neurological disorders correlates with the growing numbers of elderly - Paucity of drugs that treat these neurological disorders - Reasons for this failure - Need to reassess ... more More info
6. Discovery of Levetiracetam (Keppra(R)): The first SV2A ligand for the treatment of epilepsy (35 mins)
Play '6. Discovery of Levetiracetam (Keppra(R)): The first SV2A ligand for the treatment of epilepsy'
SpeakersDr. Henrik Klitgaard  –  UCB, Belgium
Series Drug Discovery and Development in the Neurosciences
Relevant
    extract
Levetiracetam - Antiepileptic Drug Discovery - Levetiracetam in electroshock and PTZ seizures - Protection against seizures in rat model - Levetiracetam activity in GAERS model - Impact on cognitiv... more More info
7. Anti-seizure drugs: Discovery and development (47 mins)
Play '7. Anti-seizure drugs: Discovery and development'
SpeakersDr. Roger Porter  –  Epilepsy Therapy Project, USA
Series Drug Discovery and Development in the Neurosciences
Epilepsy and Seizures
Relevant
    extract
Seizures and epilepsy - Drugs for the symptomatic treatment of seizures - Finding new Anti-Seizure Drugs is a combination of serendipity, screening and rational approaches - Drug Development - Prec... more More info
8. Disease-modifying therapies for Parkinson's disease (51 mins)
Play '8. Disease-modifying therapies for Parkinson's disease'
SpeakersDr. Todd Sherer  –  Michael J. Fox Foundation, USA
Series Drug Discovery and Development in the Neurosciences
Relevant
    extract
The need for disease-modifying therapies for Parkinson's disease - Promising targets and pathways - Genetics - Neurorestoration - Implicated biochemical pathways - Challenges for clinical translati... more More info
9. Discovery of schizophrenia drug targets from DISC1 mechanisms (20 mins)
Play '9. Discovery of schizophrenia drug targets from DISC1 mechanisms'
SpeakersDr. Atsushi Kamiya  –  Johns Hopkins University School of Medicine, USA
Series Drug Discovery and Development in the Neurosciences
Relevant
    extract
Discovery of DISC1 - Potential Therapeutics strategies based on the structure and motif of DISC1 protein - DISC1-associated pathways as drug targets - Molecular complexities of DISC1 more More info
10. Animal models for schizophrenia (33 mins)
Play '10. Animal models for schizophrenia'
SpeakersDr. Mikhail Pletnikov  –  Johns Hopkins University School of Medicine, USA
Series Drug Discovery and Development in the Neurosciences
Relevant
    extract
Animal models for schizophrenia - Animal models of psychiatric disorders - Non-genetic animals models - genetic animal models - DISC1 anima models - Weaknesses of the current animal models for schi... more More info
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