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Navigable Slide Index

1. Introduction
2. Autoimmunity
3. Etiology of autoimmune disease
4. Induction of autoimmunity: mechanisms
5. The spectrum of autoimmune diseases
6. Organ-specific and non-organ-specific disorders
7. Overlap of autoantibodies
8. Stimulating anti-thyroid antibodies
9. Placental transfer of stimulating anti-thyroid Abs
10. The spectrum of autoimmune diseases (selection)
11. Pathogenetic immune responses
12. Role of auto-Abs in autoimmune diseases
13. Anti-GBM, Goodpasture's syndrome (1)
14. Anti-GBM, Goodpasture's syndrome (2)
15. Anti-GBM disease membranes
16. Type 2 reaction
17. Anti-GBM, Goodpasture's syndrome (3)
18. Type 3 reaction: formation of immune complexes
19. SLE-ACR criteria
20. Example of rash
21. Class IV-S (A)
22. Rise in anti-dsDNA and relapse
23. Auto-Abs in lupus nephritis
24. GBM-nucleosome-antibody interaction
25. Auto-Abs to C1q: clinical associations
26. Auto-Abs to C1q: relation to disease activity (1)
27. Auto-Abs to C1q: relation to disease activity (2)
28. Pathogenicity of anti-C1q in lupus nephritis (1)
29. Pathogenicity of anti-C1q in lupus nephritis (2)
30. ANCA-associated vasculitides
31. Anti-neutrophil cytoplasmic Abs (ANCA)
32. c-ANCA, anti-Pr3 and anti-MPO
33. Pathogenetic pathways in the primary vasculitides
34. ANCA-associated vasculitis: pauci-immune
35. Clinical evidence for pathogenicity of ANCA (1)
36. Clinical evidence for pathogenicity of ANCA (2)
37. ANCA-induced PMN activation
38. MPO-ANCA are pathogenic in vivo (1)
39. MPO-ANCA are pathogenic in vivo (2)
40. Are PR3-ANCA pathogenic in vivo?
41. Nasal carriage of S. aureus and relapses of WG
42. Are ANCA pathogenic?
43. Pathogenic mechanisms of auto-Abs?

Topics Covered

• Loss of tolerance for "self"
• Immune response to "self"
• Self destruction
• Etiology of autoimmune diseases: endogenous and exogenous factors
• Mechanisms of autoimmunity
• The spectrum of autoimmune diseases
• Organ-specific and non-organ-specific disorders
• Overlap of autoantibodies
• Anti-thyroid antibodies
• Pathogenic immune responses
• Systemic autoimmune diseases
• Anti-GMB and Goodpasture's syndrome
• Anti-C1q
• ANCA-associated vasculitis

Links

Series:

• Autoimmunity

Categories:

• Clinical Practice
• Immunology

Therapeutic Areas:

• Immunology & Inflammation

Talk Citation

Publication History

• Published on October 1, 2007
• Archived on June 30, 2020

Financial Disclosures

• Prof. Cees Kallenberg has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.