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1. Introduction
2. Skeletal muscle fiber types
3. Mitochondrial reticulum in human muscle (1)
4. Mitochondrial reticulum in human muscle (2)
5. Subsarcolemmal and intermyofibrillar distribution
6. Biochemical adaptations in muscle
7. Transition between untrained and trained states
8. Mitochondrial biogenesis as a result of exercise
9. Changes in mitochondrial marker enzymes
10. Nuclei isolation procedure
11. Nuclear run-on
12. Exercise and metabolic genes transcription (1)
13. Exercise induces increase in gene transcription
14. Exercise and metabolic genes transcription (2)
15. Exercise and metabolic genes transcription (3)
16. Exercise and metabolic genes transcription (4)
17. Exercise activates transcription of different genes
18. Explaining the training response
19. Principles of protein turnover (1)
20. Principles of protein turnover (2)
21. Principles of protein turnover (3)
22. Principles of protein turnover (4)
23. The kinetics of exercise training adaptations (1)
24. The kinetics of exercise training adaptations (2)
25. The kinetics of exercise training adaptations (3)
26. Regulation occurs at multiple levels
27. An example of a metabolic priority gene
28. Prolonged exercise vs. recovery from exercise
29. Exercise-induced mitochondrial biogenesis signals
30. AMP-activated protein kinase
31. Regulation by AMP-activated protein kinase (1)
32. Regulation by AMP-activated protein kinase (2)
33. AMPK KO studies
34. Calcium/calmodulin dependent signals
35. Calcium-mediated signaling events (1)
36. Calcium-mediated signaling events (2)
37. Calcium-mediated signaling events (3)
38. Exercise-induced mitochondrial biogenesis
39. Mitochondrial biogenesis sequence
40. Summary/implications
41. References

Topics Covered

• Introduction to skeletal muscle fiber types
• Mitochondrial morphology in muscle fiber types
• Mitochondrial adaptations to exercise training
• Mitochondrial content, physical activity & aging
• Signaling to mitochondrial biogenesis
• Endurance performance & mitochondria content

Links

Series:

• Mitochondrial Biogenesis

Categories:

• Cell Biology

Talk Citation

Publication History

• Published on October 1, 2007
• Archived on May 31, 2018

Financial Disclosures

• Dr. Darrell Neufer has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.